{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T09:48:10Z","timestamp":1782467290970,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The increased circulation of enteroviruses (EVs) from July to December 2024 necessitated a retrospective analysis of hospitalized children with acute respiratory infections in Beijing, China, during 2017\u20132024. Among the 155 cases confirmed as EVs (0.67%, 155\/23,245), with peaks in a triennial pattern and predominance between July and October, 114 were EV\u2010D68, with 82 (71.93%) detected between July and October 2024. Among the 79\n                    <jats:italic>VP1<\/jats:italic>\n                    gene sequences of EV\u2010D68 classified into subclades B3 (50.63%, 40\/79) and D1 (49.37%, 39\/79) through phylogenetic analysis, 31 (77.50%, 31\/40) were B3 from 2024, and 34 (87.18%, 34\/39) were D1 from 2024. More patients infected with B3 required oxygen supplementation than those infected with D1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.042). Therefore, an epidemic of EV\u2010D68 with the co\u2010circulation of B3 and D1 was observed in 2024, with more severe disease caused by B3 than by D1, which underscores the urgent need for surveillance of EV\u2010D68.\n                  <\/jats:p>","DOI":"10.1002\/jmv.70994","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T08:17:47Z","timestamp":1779956267000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Enterovirus D68 Epidemic in Children With Acute Respiratory Infections in Beijing, China, 2017\u20132024"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8367-8995","authenticated-orcid":false,"given":"Hanhaoyu","family":"Fu","sequence":"first","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Center for Children's Health, Capital Institute of Pediatrics Capital Medical University Beijing China"},{"name":"Graduate School of Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ri","family":"De","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Center for Children's Health, Capital Institute of Pediatrics Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenzhi","family":"Han","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Center for Children's Health, Capital Institute of Pediatrics Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Jia","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Center for Children's Health, Capital Institute of Pediatrics Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Center for Children's Health, Capital Institute of Pediatrics Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Sun","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Center for Children's Health, Capital Institute of Pediatrics Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010Mei","family":"Chen","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Beijing Key Laboratory of Etiology of 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