{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T12:19:57Z","timestamp":1787660397190,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T00:00:00Z","timestamp":1786147200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20H04411"],"award-info":[{"award-number":["20H04411"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Group A rotavirus (RVA) genotype G3P[8] strains typically carry a Wa\u2010like genomic backbone, but DS\u20101\u2010like G3P[8] reassortants have disseminated globally since 2013. In Sabah, Malaysia, surveillance in 2018\u20132019 identified frequent G3P[8] strains with a short RNA electropherotype, consistent with DS\u20101\u2010like backbones. Here, we sequenced whole genomes (Illumina MiSeq) of seven representative short\u2010pattern strains (KN4, KN7, L39, L68, L116, L222, and L286) and a co\u2010circulating long\u2010pattern Wa\u2010like G3P[8] strain (L86). Six short\u2010pattern strains possessed the canonical DS\u20101\u2010like backbone I2\u2010R2\u2010C2\u2010M2\u2010A2\u2010N2\u2010T2\u2010E2\u2010H2, whereas one strain (L116) carried a Wa\u2010like VP3 genotype (M1) within an otherwise DS\u20101\u2010like genome. Whole\u2010genome phylogenies segregated the DS\u20101\u2010like strains into two lineages\u2014KN4\u2010like (with KN4, KN7, and L68) and L39\u2010like (with L39, L116, L222, and L286)\u2014that each represented different globally circulating DS\u20101\u2010like G3P[8] clades, consistent with at least two distinct introductions into Sabah. L116 VP3 shared &lt;\u200980% with the other study strains, whereas for the remaining segments this was &gt;\u200993%. Instead, L116 VP3 clustered with Wa\u2010like G12, suggesting a DS\u20101\u2010like\/Wa\u2010like intergenogroup (within backbone) reassortment event. Our findings contribute to understanding the evolutionary dynamics of globally emerging DS\u20101\u2010like G3P[8] strains.<\/jats:p>","DOI":"10.1002\/jmv.71097","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T11:52:34Z","timestamp":1786189954000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two Lineages of DS\u20101\u2010Like G3P[8] Human Rotaviruses in Sabah, Malaysia: Genetic Diversity and Evidence of Reassortment"],"prefix":"10.1002","volume":"98","author":[{"given":"Yuki","family":"Akari","sequence":"first","affiliation":[{"name":"Division of One Health, Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) Oita University Yufu Oita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lia Natasha","family":"Amit","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine and Health Sciences Universiti Malaysia Sabah Kota Kinabalu Sabah Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7885-6453","authenticated-orcid":false,"given":"Jecelyn Leaslie","family":"John","sequence":"additional","affiliation":[{"name":"Borneo Medical and Health Research Centre, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah Kota Kinabalu Sabah Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6567-9438","authenticated-orcid":false,"given":"Daisuke","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine and Health Sciences Universiti Malaysia Sabah Kota Kinabalu Sabah Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham Zefong","family":"Chin","sequence":"additional","affiliation":[{"name":"Sabah State Health Department Surveillance Sector, Public Health Division, Ministry of Health Malaysia Kota Kinabalu Sabah Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andau Konodan","family":"Mosiun","sequence":"additional","affiliation":[{"name":"Kunak District Health Office, Ministry of Health Malaysia Kunak Sabah Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0841-880X","authenticated-orcid":false,"given":"Saori","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Virology Fujita Health University School of Medicine Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurine Mumo","family":"Mutua","sequence":"additional","affiliation":[{"name":"Division of One Health, Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) Oita University Yufu Oita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibuki","family":"Sato","sequence":"additional","affiliation":[{"name":"Division of One Health, Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) Oita University Yufu Oita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimasa","family":"Maeno","sequence":"additional","affiliation":[{"name":"Department of Protozoology Institute of Tropical Medicine Nagasaki University Nagasaki Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1869-3701","authenticated-orcid":false,"given":"Kamruddin","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine and Health Sciences Universiti Malaysia Sabah Kota Kinabalu Sabah Malaysia"},{"name":"Borneo Medical and Health Research Centre, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah Kota Kinabalu Sabah Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2810-8163","authenticated-orcid":false,"given":"Satoshi","family":"Komoto","sequence":"additional","affiliation":[{"name":"Division of One Health, Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID) Oita University Yufu Oita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ1013"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2018.1960"},{"key":"e_1_2_10_4_1","first-page":"1347","volume-title":"Fields Virology","author":"Estes M. 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