{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T21:38:37Z","timestamp":1792618717442,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Human adenovirus (HAdV) is one of the causative viral pathogens of acute gastroenteritis (AGE) in children worldwide, accounting for approximately 10% of diarrheal cases. To enhance understanding of the prevalence and epidemiology of HAdV infection, we conducted a 3\u2010year molecular detection and characterization study of HAdV associated with AGE in Chiang Mai, Thailand, from 2022 to 2024. Among 1356 pediatric patients, HAdV was detected in 85 cases (6.3%). The highest HAdV infection rate was observed in 2023 (10.4%). HAdV infections were most frequently detected in children aged 3\u20134 years. Co\u2010circulation of three HAdV species, including enteric HAdV\u2010F and non\u2010enteric HAdV\u2010B and HAdV\u2010C, was detected. Among these, six genotypes were identified, including HAdV\u2010F41 (44.7%), HAdV\u2010B3 (18.8%), HAdV\u2010C1 (17.6%), HAdV\u2010C5 (11.8%), HAdV\u2010C2 (5.9%), and HAdV\u2010B7 (1.2%). Notably, the emergence of HAdV\u2010F41 was observed in 2023, accounting for 65.2% of HAdV\u2010positive cases in that year. HAdV infections occurred year\u2010round, with higher detection rates observed in June and August of 2023. In conclusion, this study demonstrates the prevalence, seasonality, and genotype diversity of HAdV infections among children with AGE in Thailand during 2022\u20132024. These findings indicate the co\u2010circulation of enteric and non\u2010enteric HAdVs in pediatric patients with AGE and provide valuable epidemiological insights for future surveillance and prevention strategies.<\/jats:p>","DOI":"10.1002\/jmv.71141","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:27:51Z","timestamp":1789039671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Emerging Trend of Notably High Prevalence of Human Enteric Adenovirus F41 Among Pediatric Patients With Acute Gastroenteritis in Thailand, 2022\u20132024"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7028-7607","authenticated-orcid":false,"given":"Kattareeya","family":"Kumthip","sequence":"first","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"},{"name":"Center of Excellence (Emerging and Re\u2010emerging Diarrheal Viruses Research Cluster) Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5546-4169","authenticated-orcid":false,"given":"Arpaporn","family":"Yodmeeklin","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"},{"name":"Center of Excellence (Emerging and Re\u2010emerging Diarrheal Viruses Research Cluster) Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2220-6435","authenticated-orcid":false,"given":"Pattara","family":"Khamrin","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"},{"name":"Center of Excellence (Emerging and Re\u2010emerging Diarrheal Viruses Research Cluster) Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4378-3861","authenticated-orcid":false,"given":"Hiroshi","family":"Ushijima","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Department of Pathology and Microbiology Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5665-3332","authenticated-orcid":false,"given":"Niwat","family":"Maneekarn","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"},{"name":"Center of Excellence (Emerging and Re\u2010emerging Diarrheal Viruses Research Cluster) Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14103465"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-024-09386-x"},{"issue":"11","key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1099\/vir.0.19497-0","article-title":"Genetic Content and Evolution of Adenoviruses","volume":"84","author":"Davison A. 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