{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:04:24Z","timestamp":1778227464657,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,5,3]],"date-time":"2017-05-03T00:00:00Z","timestamp":1493769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Neuroscience Research"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although several donor nerves can be chosen to repair avulsed brachial plexus nerve injury, available nerves are still limited. The purpose of this study is to validate whether the vagus nerve (VN) can be used as a donor. Eighteen Sprague\u2010Dawley male rats were divided into three groups (n\u2009=\u20096). The right musculocutaneous nerve (McN) was transected with differing subsequent repair. (1) HS\u2010VN group: a saphenous nerve (SN) graft\u2010end was helicoidally wrapped round the VN side (epi\u2010and perineurium was opened) with a 30\u2009\u00b0 angle, distal SN end was coapted to the McN with end\u2010to\u2010end repair. (2) EE\u2010PN group: a SN was interpositionally grafted between the transected phrenic nerve (PN) and the McN by end\u2010to\u2010end coaptation. (3) Sham control group: McN was transected and not repaired and postoperative vital signs were checked daily. At three months, electrophysiology, tetanic force, wet biceps muscle weight, and histology were evaluated. Every tested mean value in HS\u2010VN group was significantly greater than the EE\u2010PN or the sham control groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05 or <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.005). The mean recovery ratio of regenerated nerve fibers was 96% and, in HS\u2010VN group, the mean recovery ratio of CMAP was 79%. No vital signs changed in any group. There was no statistical difference (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.5) between the mean VN nerve\u2010fiber numbers of the segments proximal (2237\u2009\u00b1\u2009134) and distal (2150\u2009\u00b1\u2009156) to the VN graft\u2010attachment site. Histological analysis revealed no axon injury or intraneural scarring at any point along the VN. This study demonstrated that VN is a practical and reliable donor nerve for end\u2010to\u2010side nerve transfer. \u00a9 2017 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jnr.24074","type":"journal-article","created":{"date-parts":[[2017,5,3]],"date-time":"2017-05-03T14:16:48Z","timestamp":1493821008000},"page":"2493-2499","source":"Crossref","is-referenced-by-count":11,"title":["Repair of the musculocutaneous nerve using the vagus nerve as donor by helicoid end\u2010to\u2010side technique: an experimental study in rats"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9058-4801","authenticated-orcid":false,"given":"Ji\u2010Geng","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng\u2010Yi","family":"Shen","sequence":"additional","affiliation":[{"name":"Froedtert Health\u2010Community Memorial Hospital, Medical College of Wisconsin Milwaukee  WI 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Thayer","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhui","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"LoGiudice","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hani","family":"Matloub","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Sanger","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"},{"name":"Division of Plastic Surgery, Department of Surgery, Zablocki VA Medical Center  Milwaukee WI 53295"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin\u2010Ling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Havlik","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical College of Wisconsin Milwaukee Wisconsin 53226 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/00003086-198812000-00011","article-title":"Neurotization via the spinal accessory nerve in complete paralysis due to multiple avulsion injuries of the brachial plexus","volume":"237","author":"Allieu Y","year":"1988","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_8_3_1","first-page":"113","article-title":"Les paralysies traumatiques C5\u2010C6 et C5\u2010C6\u2010C7 du plexus brachial de I'adulte par lesions supraclaviculaires","volume":"84","author":"Alnot JY","year":"1998","journal-title":"Rev Chir Orthop Reparatrice Appar Mot"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22904"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-7221-2-12"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30088"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3171\/2016.5.SPINE151544"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-0358.59272"},{"key":"e_1_2_8_9_1","volume-title":"Surgical disorders of the peripheral nerve, 1 ed","author":"Birch R","year":"1998"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(03)00210-9"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199507000-00019"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(92)90451-T"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.5.3434"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3171\/2009.4.JNS081064"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1006759"},{"key":"e_1_2_8_16_1","first-page":"1","article-title":"Phrenic nerve transfer to treat root avulsion of brachial plexus","volume":"5","author":"Gu YD","year":"1989","journal-title":"Chin Hand Surg"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920100407"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(05)80235-9"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(94)90196-1"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(96)80349-2"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200010000-00022"},{"key":"e_1_2_8_22_1","first-page":"703","article-title":"Anatomical feasibility of vagus nerve esophageal branch transfer to the phrenic nerve","volume":"7","author":"Wang C","year":"2012","journal-title":"Neural Regen Res"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414546397"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0079552"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20840"},{"key":"e_1_2_8_26_1","first-page":"1179","article-title":"Long\u2010term impact of transfer of phrenic nerve on respiratory system of children: a clinical study of 34 cases","volume":"86","author":"Yang Y","year":"2006","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20015"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2010.04.006"},{"key":"e_1_2_8_29_1","first-page":"1","article-title":"Improved neural microcirculation and regeneration after peripheral nerve decompression in DPN rats","volume":"14","author":"Zhong W","year":"2017","journal-title":"Neurol Res"}],"container-title":["Journal of Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjnr.24074","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jnr.24074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T19:07:37Z","timestamp":1696014457000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jnr.24074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,3]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1002\/jnr.24074"],"URL":"https:\/\/doi.org\/10.1002\/jnr.24074","archive":["Portico"],"relation":{},"ISSN":["0360-4012","1097-4547"],"issn-type":[{"value":"0360-4012","type":"print"},{"value":"1097-4547","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,3]]}}}