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A substantial percentage of COVID\u201019\u2010infected individuals in specific health categories have been virtually asymptomatic, several other individuals in the same health categories have exhibited several unusual symptoms, and yet other individuals in the same health categories have fatal outcomes. It is now hypothesized that these differences in mortality rates and symptoms could be caused by a SARS\u2010CoV\u20102 virus infection acting together with one or more latent pathogen infections in certain patients, through mutually beneficial induced immune cell dysfunctions, including T\u2010cell exhaustion. A latent pathogen infection likely to be involved is the protozoan parasite\n                    <jats:italic>Toxoplasma gondii<\/jats:italic>\n                    , which infects approximately one third of the global human population. Furthermore, certain infections and cancers that cause T\u2010cell exhaustion can also explain the more severe outcomes of other COVID\u201019 patients having several disease and cancer comorbidities.\n                  <\/jats:p>","DOI":"10.1002\/jnr.24917","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T13:33:17Z","timestamp":1626701597000},"page":"2367-2376","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["A role for T\u2010cell exhaustion in Long COVID\u201019 and severe outcomes for several categories of COVID\u201019 patients"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4843-9835","authenticated-orcid":false,"given":"Kevin","family":"Roe","sequence":"first","affiliation":[{"name":"San Jose CA 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