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Typical EAE motor impairments were assessed daily and noninvasive visual evoked potentials (VEPs) were recorded at baseline and 5\u00a0weeks after immunization, with final histopathology of optic nerves (ONs). Immunized rats exhibited a relapsing\u2010remitting clinical course. Both VEP and histological abnormalities were detected in a MOG dose\u2010dependent gradient. 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