{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:13:30Z","timestamp":1772118810365,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,4,9]],"date-time":"2023-04-09T00:00:00Z","timestamp":1680998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Neuroscience Research"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Classical dynamins (DNMs) are GTPase proteins engaged in endocytosis, a fundamental process for cargo internalization from the plasma membrane. In mammals, three\n                    <jats:italic>DNM<\/jats:italic>\n                    genes are present with different expression patterns.\n                    <jats:italic>DNM1<\/jats:italic>\n                    is expressed at high levels in neurons, where it takes place in the recycling of synaptic vesicles;\n                    <jats:italic>DNM2<\/jats:italic>\n                    is ubiquitously expressed, while\n                    <jats:italic>DNM3<\/jats:italic>\n                    is found in the brain and in the testis. Due to the conservation of genes in comparison to mammals, we took advantage of a zebrafish model for functional characterization of\n                    <jats:italic>dnm1a<\/jats:italic>\n                    , ortholog of mammalian\n                    <jats:italic>DNM1<\/jats:italic>\n                    . Our data strongly demonstrated that\n                    <jats:italic>dnm1a<\/jats:italic>\n                    has a nervous tissue\u2010specific expression pattern and plays a role in the formation of both axon and synapse. This is the first in vivo study that collects evidence about the effects of\n                    <jats:italic>dnm1a<\/jats:italic>\n                    loss of function in zebrafish, thus providing a new excellent model to be used in different scientific fields.\n                  <\/jats:p>","DOI":"10.1002\/jnr.25197","type":"journal-article","created":{"date-parts":[[2023,4,9]],"date-time":"2023-04-09T14:15:16Z","timestamp":1681049716000},"page":"1345-1359","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Zebrafish\n                    <i>dnm1a<\/i>\n                    gene plays a role in the formation of axons and synapses in the nervous tissue"],"prefix":"10.1002","volume":"101","author":[{"given":"Cinzia","family":"Bragato","sequence":"first","affiliation":[{"name":"Department of Earth and Environmental Sciences, POLARIS Research Center University of Milano\u2010Bicocca  Milan 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