{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T20:11:27Z","timestamp":1774987887532,"version":"3.50.1"},"reference-count":78,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Neuroscience Research"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The interaction between major depressive disorder (MDD) and overweight\/obesity has received considerable attention owing to its widespread occurrence and the intricate biopsychological implications involved. Despite extensive research, the neural mechanisms underlying these comorbid conditions, particularly in terms of functional network connectivity (FNC), are still not well understood. This study aimed to clarify these mechanisms by utilizing resting\u2010state functional magnetic resonance imaging (rs\u2010fMRI) to examine both static and dynamic FNC. We analyzed data from 57 patients with both MDD and overweight\/obesity (MDD\u2010OW), 57 MDD patients of normal weight (MDD\u2010NW), and 44 healthy controls, using techniques such as independent component analysis, sliding window analysis, K\u2010means clustering, and graph theory. In contrast to static FNC, which showed no significant differences, dynamic FNC analysis identified four consistent states across all participants. Both MDD groups demonstrated reduced flexibility in functional coordination among these states and decreased nodal characteristics within the salience network. Notably, the MDD\u2010OW group displayed enhanced dynamic FNC between the default mode network (DMN) and the executive control network (ECN) during certain states, which was inversely associated with the severity of depressive symptoms. These results highlight the importance of altered dynamic connectivity patterns in individuals with MDD and concurrent overweight\/obesity, especially between the DMN and ECN, suggesting their potential utility as biomarkers for depressive states. This research contributes to our understanding of how comorbid overweight\/obesity affects brain network dynamics in depressive disorders and provides a basis for targeted therapeutic strategies.<\/jats:p>","DOI":"10.1002\/jnr.70001","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T05:19:14Z","timestamp":1732857554000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["RETRACTED: Aberrant Dynamic Network Connectivity Changes in Comorbid Depression and Overweight\/Obesity: Insights From the Triple Network Model"],"prefix":"10.1002","volume":"102","author":[{"given":"Zhu\u2010Qing","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Radiology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Radiology Guizhou Provincial People's Hospital  Guiyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi\u2010Peng","family":"Guo","sequence":"additional","affiliation":[{"name":"Beijing Hospital of Traditional Chinese Medicine Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1311-2004","authenticated-orcid":false,"given":"Shuang\u2010Shuang","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue\u2010Jun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10548\u2010017\u20100546\u20102"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs352"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.07.007"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291716002646"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1162\/neco.1995.7.6.1129"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsq080"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574\u2010019\u20100176\u20108"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2575"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1109\/MSP.2015.2478915"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2024.07.021"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.12.176"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112338\u201020220402\u201000253"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(03)15268\u20103"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn755"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2009.04.015"},{"key":"e_1_2_11_17_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM\u20105\u2122","author":"DSM\u20105","year":"2013"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(17)32154\u20102"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsz085"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhx008"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2011.2"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2010.00843.x"},{"issue":"11","key":"e_1_2_11_23_1","first-page":"37","article-title":"Weight Gain and Antidepressants","volume":"61","author":"Fava M.","year":"2000","journal-title":"Journal of Clinical Psychiatry"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21713"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504136102"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22104"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2019.2996"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2019.04.011"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.09.020"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.03.032"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2010.46"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044\u20108341.1959.tb00467.x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.56"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp089"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.03.027"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.12020wc3"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.13967"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2015.0071"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010021\u201001348\u2010x"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2021.08.033"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2022.106969"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264\u2010021\u201000638\u20103"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234\u2010022\u201003061\u20101"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2280(1998)31:2<125::AID-EM4>3.0.CO;2-L"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.47626\/1516\u20104446\u20102021\u20102032"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(18)31948\u20102"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009728.pub3"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23346"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682\u2010017\u20109802\u2010z"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2011.08.003"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429\u2010010\u20100262\u20100"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010018\u20100017\u20105"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbae020"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.10.026"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741\u20107015\u201011\u2010129"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.10.003"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858405285632"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1159\/000375143"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010019\u20100516\u20104"},{"key":"e_1_2_11_60_1","first-page":"386","article-title":"GRETNA: A Graph Theoretical Network Analysis Toolbox for Imaging Connectomics","volume":"9","author":"Wang J.","year":"2015","journal-title":"Frontiers in Human Neuroscience"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1017\/S003329171900028X"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682\u2010018\u20109978\u2010x"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1097\/HRP.0000000000000081"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/30918"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2014.11.002"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00191"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010021\u201001247\u20102"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.08.072"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00338.2011"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2019.109758"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2021.110401"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010021\u201001354\u2010z"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2620"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2019.109819"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2024.01.003"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2191208"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.25047"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2018.00339"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1109\/EMBC.2018.8512340"}],"updated-by":[{"DOI":"10.1002\/jnr.70074","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000}}],"container-title":["Journal of Neuroscience Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jnr.70001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T05:21:37Z","timestamp":1754112097000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jnr.70001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,29]]},"references-count":78,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/jnr.70001"],"URL":"https:\/\/doi.org\/10.1002\/jnr.70001","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/JNR.70001\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v3\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v3\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JNR.70001\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0360-4012","1097-4547"],"issn-type":[{"value":"0360-4012","type":"print"},{"value":"1097-4547","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,29]]},"assertion":[{"value":"2024-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70001"}}