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The main hallmarks of the disease include amyloid\u2010beta plaque deposits and neurofibrillary tangles consisting of hyperphosphorylated tau protein, besides other pathological features that contribute to the disease's complexity. The causes of sporadic AD are multifactorial and mostly age\u2010related and involve risk factors such as diabetes and cardiovascular or cerebrovascular disorders. Frontotemporal dementia (FTD) is another type of dementia characterized by a spectrum of behaviors, memory, and motor abnormalities and associated with abnormal depositions of protein aggregation, including tau protein. Currently approved medications are symptomatic, and no disease\u2010modifying therapy is available to halt the disease progression. Therefore, the development of multi\u2010targeted therapeutic approaches could hold promise for the treatment of AD and other neurodegenerative disorders, including tauopathies. 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