{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T02:51:56Z","timestamp":1751597516354,"version":"3.37.3"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,15]],"date-time":"2017-12-15T00:00:00Z","timestamp":1513296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The utility of standard distal bipolar electrograms (sEGM<\/jats:styled-content>s) for assessing catheter\u2010tissue contact may be obscured by the presence of far\u2010field signals. Microelectrode electrograms (mEGM<\/jats:styled-content>s) may overcome this limitation.<\/jats:p><\/jats:sec>Methods<\/jats:title>We compared 5 mEGM<\/jats:styled-content> characteristics (amplitude, frequency content, temporal signal variability, presence of injury current, and amplitude differential between bipoles) with the sEGM<\/jats:styled-content> for determining tissue contact in 20 patients undergoing ablation of typical atrial flutter. Visualization of catheter\u2010tissue contact by intracardiac echocardiography (ICE<\/jats:styled-content>) served as the gold standard for assessing contact. Correlation between electrograms and ICE<\/jats:styled-content>\u2010verified contact level was reported as percent concordance.<\/jats:p><\/jats:sec>Results<\/jats:title>Three of 5 mEGM<\/jats:styled-content> characteristics demonstrated significantly better concordance with ICE<\/jats:styled-content>\u2010verified contact level than the sEGM<\/jats:styled-content> (52% concordance with ICE<\/jats:styled-content>): mEGM<\/jats:styled-content> frequency content (59% concordance with ICE<\/jats:styled-content>, P<\/jats:italic> < .001 for comparison with sEGM<\/jats:styled-content>); mEGM<\/jats:styled-content> amplitude (concordance 59%, P<\/jats:italic> < .001); and mEGM<\/jats:styled-content> presence of injury current (56% concordance, P<\/jats:italic> = .001). Concordance of amplitude differential between mEGM<\/jats:styled-content> bipoles with ICE<\/jats:styled-content> (49%) was not significantly different than the sEGM<\/jats:styled-content> (P<\/jats:italic> = .638) whereas mEGM<\/jats:styled-content> temporal variability (39%) was significantly worse than the sEGM<\/jats:styled-content>. Using a median of all 5 mEGM<\/jats:styled-content> characteristics provided additive information (concordance with ICE<\/jats:styled-content> 64%) and was significantly better than all of the individual mEGM<\/jats:styled-content> characteristics except frequency content (P<\/jats:italic> = .976).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Microelectrode EGM<\/jats:styled-content>s (in particular frequency content, amplitude, and presence of injury current) can improve real\u2010time assessment of catheter contact compared to the use of standard bipolar EGM<\/jats:styled-content>s. Broader use of mEGM<\/jats:styled-content>s may enhance ablation efficacy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12006","type":"journal-article","created":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T12:05:40Z","timestamp":1518782740000},"page":"23-29","source":"Crossref","is-referenced-by-count":3,"title":["Use of microelectrode near\u2010field signals to determine catheter contact"],"prefix":"10.1002","volume":"34","author":[{"given":"Mathew R.","family":"Levy","sequence":"first","affiliation":[{"name":"Division of Cardiology Section of Cardiac Electrophysiology Emory University School of Medicine Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0679-860X","authenticated-orcid":false,"given":"Faisal M.","family":"Merchant","sequence":"additional","affiliation":[{"name":"Division of Cardiology Section of Cardiac Electrophysiology Emory University School of Medicine Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan J.","family":"Langberg","sequence":"additional","affiliation":[{"name":"Division of Cardiology Section of Cardiac Electrophysiology Emory University School of Medicine Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Delurgio","sequence":"additional","affiliation":[{"name":"Division of Cardiology Section of Cardiac Electrophysiology Emory University School of Medicine Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00533.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus027"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.19102\/icrm.2012.030102","article-title":"Novel Ablation Catheter Technology that Improves Mapping Resolution and Monitoring of Lesion Maturation","volume":"3","author":"Price A","year":"2012","journal-title":"J Innov Card Rhythm Manag"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.001094"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1080\/01621459.1972.10482401","article-title":"Measures of Association for Cross Classifications, IV: simplification of Asymptotic Variances","volume":"67","author":"Goodman LA","year":"1972","journal-title":"J Am Stat Assoc"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429258589"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12293"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13087"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12707"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002483"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12980"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01355.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(97)70242-4"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01135.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000070541.83326.15"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2012.02331.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.05.011"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjoa3.12006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.12006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:33:39Z","timestamp":1695688419000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.12006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,15]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1002\/joa3.12006"],"URL":"https:\/\/doi.org\/10.1002\/joa3.12006","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"type":"print","value":"1880-4276"},{"type":"electronic","value":"1883-2148"}],"subject":[],"published":{"date-parts":[[2017,12,15]]}}}