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An association between BrS and atrial tachyarrhythmias is not uncommon. However, sinus node dysfunction (<jats:styled-content style=\"fixed-case\">SND<\/jats:styled-content>) associated with BrS has not been well discussed. In this review, we focus on the association between BrS and <jats:styled-content style=\"fixed-case\">SND<\/jats:styled-content>. Based on previous reports describing clinical, epidemiological, and genetic evidence, <jats:styled-content style=\"fixed-case\">SND<\/jats:styled-content> is not a rare concomitant disorder in BrS. BrS may be a multiple conduction or arrhythmogenic disorder including not only the His\u2010Purkinje system and right ventricle, but also the sinus node and atrium, derived from ion channel mutations.<\/jats:p>","DOI":"10.1002\/joa3.12046","type":"journal-article","created":{"date-parts":[[2018,3,27]],"date-time":"2018-03-27T05:36:17Z","timestamp":1522128977000},"page":"216-221","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Brugada syndrome and sinus node dysfunction"],"prefix":"10.1002","volume":"34","author":[{"given":"Hidemori","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Juntendo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2644-6356","authenticated-orcid":false,"given":"Masataka","family":"Sumiyoshi","sequence":"additional","affiliation":[{"name":"Department of 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