{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T11:07:09Z","timestamp":1755601629216,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T00:00:00Z","timestamp":1547769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb, Inc","doi-asserted-by":"crossref","award":["#GAKF850098"],"award-info":[{"award-number":["#GAKF850098"]}],"id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Induction test of atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) is one of endpoint measures in catheter ablation (<jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content>). However, its predictive value in long\u2010term outcome remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ninety\u2010eight patients (61\u00a0years, 77 males) with persistent <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> who underwent pulmonary vein antrum isolation\u2010based <jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content> were retrospectively analyzed. We determined whether inducibility of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/atrial tachyarrhythmias (<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content>) by atrial burst pacing at the end of <jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content> and other characteristics were associated with the recurrence of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content>. Atrial burst pacing was performed with 30\u2010beat from the coronary sinus; increasing from 240 to 320\u00a0ppm. Inducibility was defined as <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> lasting \u22655\u00a0minutes following atrial burst pacing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> was induced in 50 patients (51%). During 1\u00a0year of follow\u2010up, 71 patients (72.4%) had no recurrence of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content>. A logistic regression analysis showed that female gender (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.8; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.02), multiple sessions (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.5; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.02), and early recurrence of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 5.3; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.004) were associated with clinical recurrence. <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> Inducibility was not associated with clinical recurrence (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.65). A subanalysis in patients with enlarged <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> diameter \u226545\u00a0mm, n\u00a0=\u00a040) showed that <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> inducibility was associated with recurrence (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 8.1; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.04). The positive and negative predictive values of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> inducibility for <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> recurrence were 41 and 89%, respectively. Negative predictive value was increased to 92.3% when the inducibility was defined as <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> of \u226530\u00a0seconds following atrial burst pacing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AT<\/jats:styled-content> inducibility cannot predict long\u2010term clinical recurrence in patients with persistent <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>. However, it may have a prognostic value especially in patients with enlarged <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12150","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T11:08:59Z","timestamp":1547809739000},"page":"223-229","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Predictive value of the induction test with atrial burst pacing with regard to long\u2010term recurrence after ablation in persistent atrial fibrillation"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1822-6054","authenticated-orcid":false,"given":"Shunsuke","family":"Kawai","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Graduate School of Medical Sciences Kyushu University  Fukuoka 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