{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:18:08Z","timestamp":1771633088404,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2019,4]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF<\/jats:styled-content>) in patients with acute coronary syndrome (ACS<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>A total 648 of consecutive ACS<\/jats:styled-content> patients were divided into non\u2010AF<\/jats:styled-content> and all\u2010AF<\/jats:styled-content> groups. The all\u2010AF<\/jats:styled-content> group was further subdivided into new\u2010onset AF<\/jats:styled-content> and pre\u2010existing AF<\/jats:styled-content> groups. We compared prognosis among these groups using the Cox regression analysis.<\/jats:p><\/jats:sec>Results<\/jats:title>The mean follow\u2010up period was 1.4\u00a0\u00b1\u00a01.2\u00a0years. Overall patient numbers were 538 in non\u2010AF<\/jats:styled-content> and 110 in all\u2010AF<\/jats:styled-content> groups (67 in new\u2010onset AF<\/jats:styled-content> and 43 in pre\u2010existing AF<\/jats:styled-content>). Seventy\u2010eight all\u2010cause deaths and 42 cardiac deaths were observed. New\u2010onset AF<\/jats:styled-content> had a worse prognosis than the other groups in the Kaplan\u2010Meier analysis (P<\/jats:italic>\u00a0=\u00a00.025) after observation. Cox regression analysis indicated no significant difference for all\u2010cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all\u2010AF<\/jats:styled-content> and new\u2010onset AF<\/jats:styled-content> group than in the non\u2010AF<\/jats:styled-content> group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification \u22652, and left ventricular ejection fraction (LVEF<\/jats:styled-content>) were independent predictors of all\u2010cause death. The new\u2010onset AF<\/jats:styled-content> group had the highest prevalence of Killip classification \u22652 and the lowest LVEF<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>In our study, AF<\/jats:styled-content> was not an independent predictor of all\u2010cause death, but new\u2010onset AF<\/jats:styled-content> may be associated with worse prognosis and future heart failure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12154","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T22:31:17Z","timestamp":1548369077000},"page":"182-189","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["New\u2010onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0196-6240","authenticated-orcid":false,"given":"Mizuyoshi","family":"Nagai","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Memorial Heart Center Iwate Medical University Morioka Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Itoh","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Memorial Heart Center Iwate Medical University Morioka Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Ishida","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Memorial Heart Center Iwate Medical University Morioka Iwate 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Memorial Heart Center Iwate Medical University Morioka Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00194-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00746-7"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1352"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.07.021"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi064"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2733"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2007.134486"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.06.055"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.03.011"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn579"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.990192"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.986661"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-010-0227-6"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.02.009"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.repc.2015.01.010"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199205073261906"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.70.1.8"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.10.965"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.9.969"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.111108"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.120410"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.52.153"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-012-0289-3"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-012-0242-5"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.03.018"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.repc.2013.10.017"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.09.016"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31826e1058"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.51.4.5"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.009449"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.03.027"}],"container-title":["Journal 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