{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:24:45Z","timestamp":1747149885090,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T00:00:00Z","timestamp":1550188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Left atrial (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) dilation is associated with morbidity of atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>). However, little is known about pulmonary vein (<jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>) dilation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We investigated the <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> volume in the patients with <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>We performed 3dimensional computed tomography (3D<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) in 155 patients and divided them into three groups: 19 patients without <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> (non\u2010<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> group, mean age 66\u00a0\u00b1\u00a012\u00a0years), 50 with paroxysmal <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> group, mean age 67\u00a0\u00b1\u00a08\u00a0years) and 24 with persistent <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> (Pe<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> group, mean age 64\u00a0\u00b1\u00a010\u00a0years). The absence of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> was diagnosed in patients with a cardiac implantable electronic device for at least 1\u00a0year (mean: 59\u00a0\u00b1\u00a037\u00a0months). We determined the <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> volume as the total volume from the orifice to the first branch of each <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>. According to the echocardiographic data, the <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> dimension (<jats:styled-content style=\"fixed-case\">LAD<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume index (<jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>) were largest in the Pe<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> group followed by the <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> and non\u2010<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> group. According to the morphometric data obtained on 3D\u2010<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>, the <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> volume was similar in Pe<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> groups but significantly smaller in the non\u2010<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> group (median value: 24 vs 21 vs 14\u00a0mL, respectively). According to the receiver operating characteristic curve analysis, the area under the curve for the <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> volume in the presence of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> was 0.80, and the optimum cut\u2010off value was 17\u00a0mL (sensitivity 74%, specificity 80%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> volume might be useful for predicting the presence of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> before increases in the <jats:styled-content style=\"fixed-case\">LAD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content> on echocardiography.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12158","type":"journal-article","created":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T12:38:12Z","timestamp":1550234292000},"page":"230-237","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Can an increase in the pulmonary vein volume measured by three dimensional computed tomography predict the presence of atrial fibrillation?"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9433-3484","authenticated-orcid":false,"given":"Masaaki","family":"Kurata","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Internal medicine Showa University Fujigaoka Hospital  Yokohama Kanagawa Japan"},{"name":"Department of Biochemistry Showa University Graduate School of Medicine  Yokohama Kanagawa 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