{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T21:02:33Z","timestamp":1761253353796,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T00:00:00Z","timestamp":1551916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although late gadolinium enhancement magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) allows the identification of lesions and gaps after a cryothermal balloon (<jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content>) ablation of paroxysmal atrial fibrillation (<jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>), the accuracy has not yet been well established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The subjects consisted of 10 consecutive patients who underwent a second ablation procedure among our cohort of 80 patients who underwent <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> after the <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content> ablation of <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> scar regions were compared with electroanatomical mapping during the second procedure. In the analysis, the unilateral pulmonary vein (<jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>) antrum was divided into 7 regions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The gap characterization analysis was performed in 140 regions around 40 <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>s in total. There were 16 <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> gaps around 11 <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>s (mean 1.6\u00a0\u00b1\u00a01.4\u00a0gaps\/patient) in 7 patients and 14 electrical gaps around 10 <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>s in 8 patients (mean 1.4\u00a0\u00b1\u00a01.1\u00a0gaps\/patient). The locations of 13 electrical gaps were well matched to that on the <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, whereas the remaining 1 electrical gap had not been predicted on the <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. Compared to the electrical gaps in the second procedure, the sensitivity and specificity of the <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> gaps were 93% (13 <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> gaps of 14 electrical gaps) and 98% (123 <jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> scars out of 126 electrical scars), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LGE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> can accurately localize the lesion gaps after <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content> ablation of <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12161","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T14:13:15Z","timestamp":1551967995000},"page":"190-196","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Feasibility of late gadolinium enhancement magnetic resonance imaging to detect ablation lesion gaps in patients undergoing cryoballoon ablation of paroxysmal atrial fibrillation"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9710-6973","authenticated-orcid":false,"given":"Tsuyoshi","family":"Mishima","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center  Suita, Osaka Japan"},{"name":"Cardiovascular Division National Hospital Organization Osaka National Hospital  Osaka 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