{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T14:46:13Z","timestamp":1767451573075,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T00:00:00Z","timestamp":1562803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The impact of the left atrial low\u2010voltage area (LVA) on the cardiac function improvement following ablation for atrial fibrillation (AF) is unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 49 patients with paroxysmal AF who underwent ablation, the left ventricular stroke volume index (SVI) was repeatedly measured using an impedance cardiography until 6\u00a0months after ablation. We defined the cardiac function improvement as a 20% increase in the SVI. The LVA (the area with the voltage amplitude of &lt;0.5\u00a0mV) was assessed before ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The reduced baseline SVI (&lt;33\u00a0mL\/m<jats:sup>2<\/jats:sup>) was observed in 18 (37%) patients. The SVI increased following ablation (from 36\u00a0\u00b1\u00a05 to 39\u00a0\u00b1\u00a06\u00a0mL\/m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). We observed the cardiac function improvement in 14 (29%) patients. The LVA was smaller in patients with the improved cardiac function than in those without (8.3%\u00a0\u00b1\u00a05.2% vs 14.0%\u00a0\u00b1\u00a08.5%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.026). The multivariate analysis revealed that only the LVA was independently associated with the cardiac function improvement (odds ratio, 0.878; 95% confidence interval: 0.778\u20100.991, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.036). Furthermore, LVAs of the anterior (7.9%\u00a0\u00b1\u00a07.6% vs 18.2%\u00a0\u00b1\u00a015.5%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.022), septal (12.0\u00a0\u00b1\u00a07.3% vs 20.7%\u00a0\u00b1\u00a013.8%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.031), and roof walls (6.9%\u00a0\u00b1\u00a06.0% vs 16.9%\u00a0\u00b1\u00a015.2%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.022) were smaller in patients with the improved cardiac function than in those without.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The LVA was related to the cardiac function improvement following ablation in patients with paroxysmal AF.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12221","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T13:38:58Z","timestamp":1562852338000},"page":"725-732","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Correlation between the left atrial low\u2010voltage area and the cardiac function improvement after catheter ablation for paroxysmal atrial fibrillation"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5427-5048","authenticated-orcid":false,"given":"Yosuke","family":"Nakatani","sequence":"first","affiliation":[{"name":"Second Department of Internal Medicine University of Toyama Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamotsu","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine University of Toyama Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine University of Toyama Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Tsujino","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine University of Toyama Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Kataoka","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine University of Toyama Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiro","family":"Nishida","sequence":"additional","affiliation":[{"name":"Nishida Medical Clinic Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Mizumaki","sequence":"additional","affiliation":[{"name":"Alpen Murotani Clinic Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Kinugawa","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine University of Toyama Toyama 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