{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:53:30Z","timestamp":1778910810195,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study aimed to analyze the burden and impact of cardiac arrhythmias in adult patients hospitalized with asthma exacerbation using the nationwide inpatient database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used the National Inpatient Sample (NIS) database (2010\u20102014) to identify arrhythmias in asthma\u2010related hospitalization and its impact on inpatient mortality, hospital length of stay (LOS), and hospitalization charges. We also used multivariable analysis to identify predictors of in\u2010hospital arrhythmia and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 12,988,129 patients hospitalized with primary diagnosis of asthma; among them, 2,014,459(16%) patients had cardiac arrhythmia. The most frequent arrhythmia identified is atrial fibrillation (AFib) (8.95%). The AFib and non\u2010AFib arrhythmia group had higher mortality (3.40% &amp; 2.22% vs 0.74%), mean length of stay (LOS) (5.9 &amp; 5.4 vs 4.2\u00a0days), and hospital charges ($53,172 &amp; $51,105 vs $34,585) as compared to the non\u2010arrhythmia group (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.005). Predictors of arrhythmia in asthma\u2010related hospitalization were history of PCI or CABG, valvular heart disease, congestive heart failure (CHF), and acute respiratory failure. Predictors of higher mortality in arrhythmia group were acute respiratory failure, sepsis, and acute myocardial infarction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Around 16% of adult patients hospitalized with asthma exacerbation experience arrythmia (mostly AFib 8.95%). The presence of arrhythmias was associated with higher in\u2010hospital mortality, LOS, and hospital charges in hospitalized asthmatics.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12452","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T15:09:44Z","timestamp":1605625784000},"page":"113-120","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Burden and impact of arrhythmias in asthma\u2010related hospitalizations: Insight from the national inpatient sample"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5867-1929","authenticated-orcid":false,"given":"Muhanad","family":"Taha","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Detroit Medical Centre\/Wayne State University Detroit MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tushar","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Detroit Medical Centre\/Wayne State University Detroit MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Shokr","sequence":"additional","affiliation":[{"name":"Cardiology Department Leon H. Charney Division of Cardiology, Cardiac Electrophysiology NYU Langone Health New York University Grossman School of Medicine New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditi","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Detroit Medical Centre\/Wayne State University Detroit MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazen","family":"Taha","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Cairo University Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lobelia","family":"Samavati","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Critical Care and Sleep Division Wayne State University Detroit MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"2016\u20132018 National Health Interview Survey (NHIS)."},{"key":"e_1_2_9_3_1","unstructured":"CDC\/NCHS. 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