{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:29:51Z","timestamp":1791336591072,"version":"4.3.1"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Early recurrences of atrial arrhythmias (ERAAs) after ablation may require therapeutic intervention. The optimal medical therapy that prevents ERAAs requires clarification. This study aimed to compare the incidence of ERAAs between patients who received or did not receive bisoprolol transdermal patches (BTPs) at 3\u00a0months postablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This single\u2010center retrospective study enrolled 203 consecutive patients with paroxysmal atrial fibrillation (AF) who had undergone their first ablation, comprising 59 in the BTP group and 144 in the non\u2010BTP group. Follow\u2010up assessments were conducted monthly for 3\u00a0months. We evaluated the incidence of ERAAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the initial 1\u2010week observational period, the rate of ERAAs was lower in the BTP group (5.0%) than that in the non\u2010BTP group (18.8%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.013). At 3\u00a0months postablation, the rate of ERAAs was lower in the BTP group (6.8%) than that in the non\u2010BTP group (25.7%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.002). The cumulative freedom from ERAAs was significantly lower in the BTP group than in the non\u2010BTP group (log\u2010rank: <jats:italic>P<\/jats:italic>\u00a0=\u00a0.003). Administering BTPs was an independent factor that protected against ERAAs (odds ratio 0.181, [95% confidence interval 0.059\u20100.559], <jats:italic>P<\/jats:italic>\u00a0=\u00a0.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>BTPs may prevent ERAAs after ablation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12538","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T07:53:08Z","timestamp":1620114788000},"page":"607-615","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of bisoprolol transdermal patch on early recurrence during the blanking period after atrial fibrillation ablation"],"prefix":"10.1002","volume":"37","author":[{"given":"Yuya","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Akashi Medical Center Akashi Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-9490","authenticated-orcid":false,"given":"Masaru","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Akashi Medical Center Akashi Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoo","family":"Fujioka","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Akashi Medical Center Akashi Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Kintsu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Akashi Medical Center Akashi Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsubasa","family":"Noda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Akashi Medical Center Akashi Hyogo 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