{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T14:18:38Z","timestamp":1771510718437,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study aimed to investigate the correlation between left atrial low\u2010voltage areas (LVAs) and an arrhythmogenic superior vena cava (SVC) and the impact on the efficacy of an empiric SVC isolation (SVCI) along with a pulmonary vein isolation (PVI) of non\u2010paroxysmal atrial fibrillation (non\u2010PAF) with or without LVAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively enrolled 153 consecutive patients with non\u2010PAF who underwent a PVI alone (n\u00a0=\u00a051) or empiric PVI plus an SVCI (n\u00a0=\u00a0102). Left atrial voltage maps were constructed during sinus rhythm to identify the LVAs (&lt;0.5\u00a0mV). An arrhythmogenic SVC was defined as firing from the SVC and an SVC associated with the maintenance of AF\u2010like rapid SVC activity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>An arrhythmogenic SVC and LVAs were identified in 28% and 65% of patients with a PVI alone and 36% and 73% of patients with a PVI plus SVCI, respectively (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.275 and <jats:italic>P<\/jats:italic>\u00a0=\u00a0.353). In the multivariate analysis a female gender, higher pulmonary artery systolic pressure (PAPs), and arrhythmogenic SVC were associated with the presence of LVAs. In the PVI plus SVCI strategy, there was no significant difference in the atrial tachyarrhythmia\/AF\u2010free survival between the patients with and without LVAs after initial and multiple sessions (50% vs. 61%; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.386, 73% vs. 79%; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.530), however, differences were observed in the PVI alone group (27% vs. 61%; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.018, 49% vs. 78%; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.046).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of LVAs was associated with an arrhythmogenic SVC. An SVCI may have the potential to compensate for an impaired outcome after a PVI in non\u2010PAF patients with LVAs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12552","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T07:40:20Z","timestamp":1621323620000},"page":"965-974","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["An impact of superior vena cava isolation in non\u2010paroxysmal atrial fibrillation patients with low voltage areas"],"prefix":"10.1002","volume":"37","author":[{"given":"Takuya","family":"Omuro","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4060-7195","authenticated-orcid":false,"given":"Yasuhiro","family":"Yoshiga","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Ueyama","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiko","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayoshi","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironori","family":"Ishiguchi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Hisaoka","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeki","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eum120"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408288"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-013-9838-y"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.001251"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.003382"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13019"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.117.005405"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux082"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12681"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01577.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-016-0198-2"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun077"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2014.10.005"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151289.73085.36"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-0951"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.255026"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2013.05.025"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13122"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.07.003"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2015.02.020"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-014-9954-3"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-020-00779-x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.10.023"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw167"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.06.016"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.03.030"},{"key":"e_1_2_10_28_1","first-page":"775","article-title":"Ablation index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target values","volume":"19","author":"Das M","year":"2017","journal-title":"Europace"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.12552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/joa3.12552","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.12552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:47:44Z","timestamp":1693356464000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.12552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,18]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/joa3.12552"],"URL":"https:\/\/doi.org\/10.1002\/joa3.12552","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"value":"1880-4276","type":"print"},{"value":"1883-2148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,18]]},"assertion":[{"value":"2021-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}