{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T13:49:39Z","timestamp":1772372979798,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T00:00:00Z","timestamp":1646352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In a stressful situation like acute coronary syndrome (ACS), the occurrence of the first episode of atrial fibrillation is more frequent. The impact of the timing occurrence of AF new\u2010onset (nAF) in the setting of ACS is still debatable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Multicenter retrospective study based on the Acute Coronary Syndrome Portuguese National Registry, including 29\u00a0851 patients admitted for ACS between 1\/10\/2010 and 4\/09\/2019. The group with early nAF \u2010 nAF in the first 48\u00a0h of hospitalization; and late nAF \u2010 patients with nAF after the first 48\u00a0h of in\u2010hospital admission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>New\u2010onset AF was identified in 1067 patients, nonetheless, just 38.1% had late nAF. The group with late nAF presented more cardiovascular comorbidities and worse left ventricular ejection fraction. Late nAF patients received more anti\u2010arrhythmic therapy, and early nAF had a higher beta\u2010block prescription. Early nAF had higher rates of in\u2010hospital complications, on the other hand, late nAF group exhibited more mortality and readmission at one year follow\u2010up. Multiple logistic regression revealed that symptoms onset to the first medical contact time, admission hemoglobin &lt;12\u00a0g\/dl, right bundle branch block at admission, and diuretic therapy during the hospitalization for ACS were predictors of late nAF in ACS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ACS population could be divided by the timing of nAF occurrence into the two groups with different characteristics, therapeutic approaches, and outcomes. Late nAF patients had a worse prognosis at 1\u00a0year follow\u2010up, however, the early nAF group had more major adverse cardiac events during the hospitalization for ACS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12689","type":"journal-article","created":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T06:56:04Z","timestamp":1646463364000},"page":"299-306","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Early and late new\u2010onset of atrial fibrillation in acute coronary syndromes: Their differences in mortality and cardiac event"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5785-0124","authenticated-orcid":false,"given":"Helder","family":"Santos","sequence":"first","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Santos","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7908-4061","authenticated-orcid":false,"given":"In\u00eas","family":"Almeida","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia B.","family":"Paula","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Almeida","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Chin","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lurdes","family":"Almeida","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de CardiologiaCentro Hospitalar Barreiro\u2010Montijo EPE  Barreiro Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Portuguese Registry of Acute Coronary Syndromes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn579"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-014-0688-5"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-012-0289-3"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu298"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy462"},{"issue":"7","key":"e_1_2_9_7_1","first-page":"563","article-title":"Portuguese registry of acute coronary syndromes (ProACS): 15 years of a continuous and prospective registry","volume":"37","author":"Tim\u00f3teo AT","year":"2018","journal-title":"Revista Portuguesa de Cardiologia"},{"issue":"1","key":"e_1_2_9_8_1","first-page":"35","article-title":"Atrial fibrillation in acute coronary syndrome","volume":"5","author":"Rubenstein JC","year":"2012","journal-title":"J Atrial Fibril"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2012.05.024"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1586\/erc.10.61"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.111108"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20603"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003319719867542"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.04.096"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003319720908760"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2007.134486"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.12689","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/joa3.12689","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.12689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T06:57:58Z","timestamp":1692255478000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.12689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,4]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/joa3.12689"],"URL":"https:\/\/doi.org\/10.1002\/joa3.12689","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"value":"1880-4276","type":"print"},{"value":"1883-2148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,4]]},"assertion":[{"value":"2021-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}