{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:51:36Z","timestamp":1787507496465,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Persistent atrial fibrillation (AF) is associated with high recurrence rates of AF and atypical atrial flutters or tachycardia (AFT) postablation. Laser balloon (LB) ablation of the pulmonary vein (PV) ostia has similar efficacy as radiofrequency wide area circumferential ablation (RF\u2010WACA); however, an approach of LB wide area circumferential ablation (LB\u2010WACA) may further improve success rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate freedom from atrial tachyarrhythmia (AFT\/AF) recurrence postablation using RF\u2010WACA versus LB\u2010WACA in persistent AF patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective multicenter study. Patients were followed for up to 24\u00a0months via office visits, Holter, and\/or device monitoring. The primary endpoint was freedom from AFT\/AF after a single ablation procedure. Secondary endpoints included freedom from AF, freedom from AFT, first\u2010pass isolation of all PVs, and procedural complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Two hundred and four patients were studied (LB\u2010WACA:\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0103; RF\u2010WACA:\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0101). Patients\u2019 baseline characteristics were similar except patients in the RF\u2010WACA group were older (64 vs. 68,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.03). First\u2010pass isolation was achieved more often during LBA (LB\u2010WACA: 88% vs. RF\u2010WACA 75%;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.04). Procedure (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.36), LA dwell (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.41), and fluoroscopy (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.44) time were similar. The mean follow\u2010up was 506\u2009\u00b1\u2009279\u2009days. Sixty\u2010six patients had arrhythmic events including 24 AFT and 59 AF recurrences. LB\u2010WACA group had higher arrhythmia\u2010free survival (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.009) after single ablation procedures. In the multivariate Cox regression model, RF\u2010WACA was associated with a higher recurrence of AFT compared with LB\u2010WACA (Adjusted HR 3.16 [95% CI: 1.13\u20138.83];\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LB\u2010WACA was associated with higher freedom from atrial arrhythmias mostly driven by the lower occurrence of AFT compared with RF\u2010WACA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.12722","type":"journal-article","created":{"date-parts":[[2022,5,7]],"date-time":"2022-05-07T01:59:18Z","timestamp":1651888758000},"page":"336-345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Wide area circumferential ablation for pulmonary vein isolation using radiofrequency versus laser balloon ablation"],"prefix":"10.1002","volume":"38","author":[{"given":"Jamario","family":"Skeete","sequence":"first","affiliation":[{"name":"Division of Cardiology Rush University Medical Center  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parikshit S.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Division of Cardiology Rush University Medical Center  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kenigsberg","sequence":"additional","affiliation":[{"name":"Florida Heart Rhythm Specialists Westside Medical Center  Fort Lauderdale Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Pietrasik","sequence":"additional","affiliation":[{"name":"Division of Cardiology Cook County Health  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed 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