{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:24:11Z","timestamp":1747149851058,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T00:00:00Z","timestamp":1678060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Electrophysiological study can help in the diagnosis of arrhythmic syncope. According to the electrophysiological study finding, the prognosis of patients with syncope is still a matter of study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to assess the survival of patients undergoing electrophysiological study according to their findings and to identify clinical and electrophysiological independent predictors of all\u2010cause mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study included patients with syncope who underwent electrophysiological study from 2009 to 2018. A Cox logistic regression analysis was performed to identify independent prognostic factors for all\u2010cause mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 383 patients in our study. During a mean follow\u2010up of 59\u2009months, 84 (21.9%) patients died. The split His group had the worst survival compared with the control group, followed by sustained ventricular tachycardia and HV interval\u2009\u2265\u200970\u2009ms, respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.001; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03). The supraventricular tachycardia group showed no differences compared with the control group (<jats:italic>p<\/jats:italic>\u00a0=\u2009.87). In the multivariate analysis, independent predictors of all\u2010cause mortality were Age (OR 1.06; 1.03\u20131.07; <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.001); congestive heart failure (OR 1.82; 1.05\u20133.15; <jats:italic>p<\/jats:italic>\u00a0=\u2009.033); split His (OR 3.7; 1.27\u201310.80; <jats:italic>p<\/jats:italic>\u00a0=\u2009.016); and sustained ventricular tachycardia (OR 1.84; 1.02\u20133.32; <jats:italic>p<\/jats:italic>\u00a0=\u2009.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Split His, sustained ventricular tachycardia, and HV interval\u2009\u2265\u200970\u2009ms groups had worse survivals when compared to the control group. Age, congestive heart failure, split His, and sustained ventricular tachycardia were independent predictors for all\u2010cause mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12836","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T09:05:11Z","timestamp":1678093511000},"page":"121-128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Electrophysiological study as a predictor of mortality in unexplained syncope"],"prefix":"10.1002","volume":"39","author":[{"given":"Javier","family":"Pinos","sequence":"first","affiliation":[{"name":"Cardiology Institute of Rio Grande Do Sul University Foundation of Cardiology  Porto Alegre Brazil"},{"name":"Hospital del Rio  Cuenca Ecuador"},{"name":"Universidad de Cuenca  Cuenca Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo Glotz","family":"De\u00a0Lima","sequence":"additional","affiliation":[{"name":"Cardiology Institute of Rio Grande Do Sul University Foundation of Cardiology  Porto Alegre Brazil"},{"name":"Federal University of Health Sciences of Porto Alegre  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Sant'Anna","sequence":"additional","affiliation":[{"name":"Cardiology Institute of Rio Grande Do Sul University Foundation of Cardiology  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Lapa","family":"Kruse","sequence":"additional","affiliation":[{"name":"Cardiology Institute of Rio Grande Do Sul University Foundation of Cardiology  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Ant\u00f4nio Vinciprova","family":"Dall'Agnese","sequence":"additional","affiliation":[{"name":"Federal University of Health Sciences of Porto Alegre  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Henrique Torres","family":"Tietz","sequence":"additional","affiliation":[{"name":"Federal University of Health Sciences of Porto Alegre  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8232-3310","authenticated-orcid":false,"given":"Marco Aur\u00e9lio Lumertz","family":"Saffi","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas de Porto Alegre  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiago Luiz Luz","family":"Leiria","sequence":"additional","affiliation":[{"name":"Cardiology Institute of Rio Grande Do Sul University Foundation of Cardiology  Porto Alegre 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