{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:24:15Z","timestamp":1747149855567,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T00:00:00Z","timestamp":1683072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Z141100002114050"],"award-info":[{"award-number":["Z141100002114050"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The atrial fibrillation better care (ABC) pathway is a simple, comprehensive framework that facilitates provision of integrated care for atrial fibrillation (AF) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We evaluated management of AF patients in a secondary prevention cohort using the ABC pathway and examined the impact of ABC adherence on clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Chinese Patients with Atrial Fibrillation registry is a prospective registry conducted in 44 sites across China between October 2014 and December 2018. The primary outcome was the composite of all\u2010cause mortality\/any thromboembolism (TE), all\u2010cause death, any TE and major bleeding at 1\u2009year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 6420 patients, 1588 (24.7%) had a prior stroke or transient ischemic attack and were identified as the secondary prevention cohort. After excluding 793 patients due to insufficient data, 358 (22.5%) were ABC compliant and 437 (27.5%) ABC noncompliant. ABC adherence was associated with a significantly lower risk of the composite outcome of all\u2010cause death\/TE, odds ratio (OR) 0.28 (95% confidence interval [CI]: 0.11\u20130.71) and all\u2010cause death, OR 0.29 (95% CI: 0.09\u20130.90). Significant differences were not observed for TE, OR 0.27 (95% CI: 0.06\u20131.27) and major bleeding, OR 2.09 (95% CI: 0.55\u20137.97). Age and prior major bleeding were significant predictors of ABC noncompliance. Health\u2010related quality of life (QOL) was higher in the ABC compliant group versus the noncompliant group (EQ score 0.83\u2009\u00b1\u20090.17 vs. 0.78\u2009\u00b1\u20090.20; <jats:italic>p<\/jats:italic>\u2009=\u2009.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ABC pathway adherence in secondary prevention AF patients was associated with a significantly lower risk of the composite outcome of all\u2010cause death\/TE and all\u2010cause death, as well as better health\u2010related QOL.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.12862","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T07:45:40Z","timestamp":1683099940000},"page":"388-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of the <scp>ABC<\/scp> pathway on clinical outcomes in a secondary prevention population of Chinese patients with atrial fibrillation: A report from the Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (<scp>ChiOTEAF<\/scp>) registry"],"prefix":"10.1002","volume":"39","author":[{"given":"Ameenathul M.","family":"Fawzy","sequence":"first","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital  Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6762-3187","authenticated-orcid":false,"given":"Agnieszka","family":"Kotalczyk","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital  Liverpool UK"},{"name":"Department of Cardiology, Congenital Heart Diseases and Electrotherapy Silesian Centre for Heart Diseases, Medical University of Silesia  Zabrze Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7626-7751","authenticated-orcid":false,"given":"Yutao","family":"Guo","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital  Liverpool UK"},{"name":"Department of Pulmonary Vessel and Thrombotic Disease Sixth Medical Centre, Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Second Medical Centre, Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7566-1626","authenticated-orcid":false,"given":"Gregory Y. H.","family":"Lip","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science University of Liverpool Liverpool John Moores University and Liverpool Heart &amp; Chest Hospital  Liverpool UK"},{"name":"Department of Cardiology, Congenital Heart Diseases and Electrotherapy Silesian Centre for Heart Diseases, Medical University of Silesia  Zabrze Poland"},{"name":"Danish Center for Clinical Health Services Research, Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the ChiOTEAF Registry Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,3]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.10.1760"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.017084"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.06.030"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011139"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-014-0195-y"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2017.153"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1739411"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/A\u20101515\u20109630"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-020191"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JACASI.2022.01.007"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut373"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01204.x"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-8-13"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2016.11.016"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023797"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S187656"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.03.053"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-2099"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afv156"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.762245"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/FCVM.2022.856222"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101757"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916\u2010022\u201002526\u20107"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.12862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T07:41:58Z","timestamp":1692517318000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.12862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,3]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/joa3.12862"],"URL":"https:\/\/doi.org\/10.1002\/joa3.12862","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"type":"print","value":"1880-4276"},{"type":"electronic","value":"1883-2148"}],"subject":[],"published":{"date-parts":[[2023,5,3]]},"assertion":[{"value":"2023-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}