{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T19:02:00Z","timestamp":1788289320178,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016175","name":"Chulabhorn Royal Academy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016175","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Long\u2010COVID syndrome has become a new health concern. Many major clinical centers have experienced more patients with symptoms suggestive of autonomic dysfunction, especially postural orthostatic tachycardia syndrome (POTS) following COVID\u201019. However, there is a lack of information regarding the incidence and associated factors in Asian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retro\u2010prospective study was conducted to evaluate patients with symptoms suggestive of POTS or other autonomic dysfunctions. These symptoms last at least 3\u2009months after PCR\u2010proven COVID\u201019. Exclusion criteria were age under 18\u2009years old, pregnancy, and pre\u2010COVID\u201019 autonomic dysfunction symptoms. Patients with a symptom severity score greater than two were assessed with blood tests, 24\u2010h Holter, 24\u2010h ambulatory blood pressure, echocardiogram, and head\u2010up tilt table (HUTT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven hundred ninety\u2010three patients were interviewed at 146\u2009\u00b1\u200937\u2009days after COVID\u201019. The majority of patients were middle\u2010aged females (53%). Of those, 15 patients had the symptom severity score greater than 2. Out of those 15 patients, 12 had positive HUTT (1 demonstrating POTS, 10 neurocardiogenic syncope, and 1 orthostatic hypotension). Among those with positive HUTT patients, C\u2010reactive protein (CRP) was significantly higher (OR 1.01; <jats:italic>p<\/jats:italic>\u2010value 0.041). Fatigue and dyspnea on exertion were the two most complaint symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study shows the incidence of autonomic dysfunction and POTS is 1.5% (12\/793) and 0.1% POTS (1\/793), respectively, in a primary care setting (among general post\u2010COVID\u201019 patients). The most common symptoms for these patients were fatigue and dyspnea.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.13001","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T06:22:59Z","timestamp":1707286979000},"page":"230-236","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Postural orthostatic tachycardia syndrome and other autonomic dysfunctions following COVID\u201019: Incidence, characteristics, and associated factors"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2702-2731","authenticated-orcid":false,"given":"Chonthicha","family":"Tanking","sequence":"first","affiliation":[{"name":"Cardiovascular Unit Chulabhorn Hospital  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanokporn","family":"Lakkananurak","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit Chulabhorn Hospital  Bangkok 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of ongoing symptoms following coronavirus (COVID\u201019) infection in the UK\u2014Office for National Statistics [Internet].2022Available 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