{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:37:30Z","timestamp":1764333450122,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Laser balloon (LB) pulmonary vein isolation (PVI) is an established ablation technique for atrial fibrillation (AF). We report long\u2010term follow\u2010up and procedural data of LB\u2010PVI and we compare the first and second LB generation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergoing LB ablation with first\u2010 (LB1) or second\u2010generation LB (LB2) for AF were retrospectively enrolled and divided into two groups. Procedural endpoint was complete PVI. Clinical success was defined as no recurrence of AF\/atrial tachycardia after a 90\u2009days blanking period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>538 patients were included (age 66\u2009\u00b1\u200910\u2009years, 58% paroxysmal AF), 427 in LB1 and 111 in LB2. 2079 PVs were targeted and 2073 (99.7%) were successfully isolated; 2027 (97.5%) using solely the LB. Additional touch\u2010up ablation was limited (46 PVs; 2.2%) with no difference between the groups. Procedural (LB1: 120\u2009\u00b1\u200933\u2009minutes vs. LB2: 99\u2009\u00b1\u200922\u2009min; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and fluoroscopy time (LB1: 11.2\u2009\u00b1\u20095\u2009min vs. LB2: 8.5\u2009\u00b1\u20093\u2009min; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) were shorter with LB2. The complication rate was 8.9% (LB1: 10.1% vs. LB2: 4.5%; <jats:italic>p<\/jats:italic>\u2009=\u2009.067) with most complications resulting from the access site (21\/48). Overall freedom from AF after 1\u2010year was 73.7% (paroxysmal AF: 76.9%; persistent AF: 69.3%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) with no difference between the groups (LB1: 73.4% vs. LB2: 74.7%; <jats:italic>p<\/jats:italic>\u2009=\u2009.491).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LB showed a high efficacy and acceptable safety, with numerically lower complication rates with the second\u2010generation LB. Procedure and fluoroscopy times were shorter with LB2. Overall, 73.7% of patients were free from AF at 1\u2010year, with comparable results among both generations.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.13088","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T09:49:28Z","timestamp":1718358568000},"page":"839-848","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Long\u2010term follow\u2010up of patients treated with laser balloon for atrial fibrillation: A high volume center experience with the first\u2010 and second\u2010generation laser balloon"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5234-744X","authenticated-orcid":false,"given":"Lukas","family":"Urbanek","sequence":"first","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Bordignon","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Tohoku","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Hirokami","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2610-1435","authenticated-orcid":false,"given":"Takahiko","family":"Nagase","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute  Fuchushi Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojie","family":"Chen","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4188-3447","authenticated-orcid":false,"given":"David","family":"Schaack","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. R. Julian","family":"Chun","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Agaplesion Markus\u2010Krankenhaus  Frankfurt\/M Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"373","article-title":"2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio\u2010Thoracic Surgery (EACTS)","author":"Hindricks G","year":"2020","journal-title":"Eur Heart J"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602014"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.07.036"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.117.005767"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.840587"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.01.019"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.009294"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13692"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12192"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euab085"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa406"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13698"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11051166"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2010.01798.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.09.029"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15729"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.13088","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T06:54:07Z","timestamp":1723445647000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.13088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,14]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1002\/joa3.13088"],"URL":"https:\/\/doi.org\/10.1002\/joa3.13088","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"type":"print","value":"1880-4276"},{"type":"electronic","value":"1883-2148"}],"subject":[],"published":{"date-parts":[[2024,6,14]]},"assertion":[{"value":"2023-12-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}