{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:43:58Z","timestamp":1791229438668,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Cardiovascular implantable electronic devices can detect atrial high\u2010rate episodes (AHREs). However, the predictors of clinically relevant AHREs have not been well identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study included 145 patients (median age 64.5\u2009\u00b1\u200916.4\u2009years, 53.1% females) without atrial fibrillation (AF) from December 2020 to January 2022. AHREs were defined as a programmed atrial detection rate &gt;190 beats per minute. Cox regression analysis was used to identify the risk factors of AHREs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During 6\u2009months of follow\u2010up, AHREs occurred in 30.3% of patients. Multivariable Cox regression analysis showed factors related to development of AHREs including using anti\u2010arrhythmic drugs (AAD) before implantation (Hazard ratio (HR) 7.71; 95% confidence interval [95% CI], 2.58\u201323.02, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), history of paroxysmal supraventricular tachycardia (PSVT; HR 2.45; [95% CI], 1.18\u20135.09, <jats:italic>p<\/jats:italic>\u2009=\u2009.016), the percentage of premature atrial contraction (PAC) on 24\u2010h Holter electrocardiogram (ECG) monitoring (HR 1.008; [95% CI], 1.003\u20131.014, <jats:italic>p<\/jats:italic>\u2009=\u2009.003), and left ventricular global longitudinal strain (GLS\u2010LV; HR 0.92;[95% CI], 0.84\u20130.99, <jats:italic>p<\/jats:italic>\u2009=\u2009.049).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study showed that a history of PSVT and using AAD, the percentage of PAC on 24\u2010h Holter ECG monitoring, and GLS\u2010LV were the independent predictors of new\u2010onset AHREs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.13143","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T07:34:01Z","timestamp":1725348841000},"page":"1158-1164","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The incidence and risk factors of atrial high\u2010rate episodes in patients with a dual\u2010chamber pacemaker"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6561-6813","authenticated-orcid":false,"given":"Son Khac","family":"Le Nguyen","sequence":"first","affiliation":[{"name":"Department of Arrhythmia Treatment Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dung Ngoc","family":"Kieu","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Treatment Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phuong Le Uyen","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Treatment Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuong Khac Thien","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Treatment Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-2958","authenticated-orcid":false,"given":"Toan Quang","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieu","family":"Van Ly","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sy","family":"Van Hoang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cho Ray Hospital  Ho Chi Minh City Vietnam"},{"name":"Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh City  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3289-1946","authenticated-orcid":false,"given":"Thuc Tri","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Arrhythmia Treatment Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Atrial fibrillation StatPearls treasure Island (FL): StatPearls publishing copyright \u00a9 2022","author":"Nesheiwat 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