{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:24:07Z","timestamp":1774311847513,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>High\u2010density (HD) substrate mapping may increase success of catheter ablation targeting ventricular tachycardia (VT). However, despite its use, recurrent VT is not uncommon. We aim to investigate factors that are associated with outcomes after HD mapping\u2010guided substrate ablation procedures for VT in patients with ischemic cardiomyopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Observational cohort study includes patients with ischemic heart disease who underwent HD mapping\u2010guided substrate ablation of VT. Baseline and procedural characteristics were associated with outcomes after VT ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>VT ablation employing HD mapping was performed in 80 patients. Median follow\u2010up was 2.3\u2009years. VT\u2010free survival at one, two, and five years were 65%, 49%, and 40%. One\u2010, two\u2010, and five\u2010year implantable cardioverter defibrillator (ICD) shock\u2010free survival rates were 90%, 81%, and 70%. Complications occurred in 3 patients (3.8%, 1 vascular, 2 tamponades). Left ventricular ejection fraction (LVEF) and 45\u2009W (vs. 35\u2009W) ablation power were associated with VT\u2010free survival. High ablation power was also associated with shock\u2010free survival. All\u2010cause mortality during follow\u2010up was associated with higher age, the presence of chronic obstructive pulmonary disease (COPD), LVEF, and urgent ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with ischemic cardiomyopathy that had HD substrate mapping\u2010guided VT ablation, ablation power was associated with both VT\u2010free and shock\u2010free survival, underlining the importance of effective target elimination. All\u2010cause mortality during follow\u2010up was associated with several factors (age, COPD, LVEF, and urgent vs. elective ablation), which could be used to guide patient selection for VT ablation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/joa3.13175","type":"journal-article","created":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T03:35:31Z","timestamp":1730518531000},"page":"1442-1451","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictors of long\u2010term success after high\u2010density mapping\u2010guided substrate ablation procedures for ventricular tachycardia in patients with ischemic cardiomyopathy"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7880-3730","authenticated-orcid":false,"given":"J. C.","family":"Balt","sequence":"first","affiliation":[{"name":"St. Antonius Hospital  Nieuwegein The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0503-8791","authenticated-orcid":false,"given":"B. G. S.","family":"Abeln","sequence":"additional","affiliation":[{"name":"St. Antonius Hospital  Nieuwegein The Netherlands"},{"name":"Amsterdam University Medical Centers  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. F.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"St. Antonius Hospital  Nieuwegein The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. C. E. 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