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Whether surgical intervention for arrhythmogenic MVP (aMVP) reduces VA and SCD risk remains unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature review was conducted using the PubMed database in December 2024. Studies documented in English were included if patients had undergone mitral valve (MV) surgery (MVS; repair or replacement) for MVP with documented rates of VA or SCD pre\u2010 and postintervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen identified studies (8 cohort and 8 case studies) comprised 1233 patients (receiving medical or surgical treatment) with a pooled mean age of 61.5\u2009years and 41.9% being female. A total of 657 MVP patients underwent MVS. Seven cohort studies reported rates of VA pre\u2010 and postintervention, with six of these and all case studies reporting a significant reduction. The remaining cohort study reported a reduction in SCD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This systematic review indicates a reduction in VA following current guideline\u2010directed MVS for MVP. However, a residual risk of VA and SCD may remain postintervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70108","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T02:49:50Z","timestamp":1752720590000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Arrhythmogenic mitral valve prolapse\u2014a systematic review of ventricular arrhythmia and sudden cardiac death outcomes before and after mitral valve surgery"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0182-2634","authenticated-orcid":false,"given":"James N.","family":"Cameron","sequence":"first","affiliation":[{"name":"Department of Cardiology Austin Health  Melbourne Victoria Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences University of Melbourne  Melbourne Victoria 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