{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:59:25Z","timestamp":1761663565863,"version":"build-2065373602"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2025,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Lead\u2010related infective endocarditis is a serious complication of implantable cardioverter\u2010defibrillators (ICDs), especially in patients with advanced heart failure who are poor surgical candidates. Management of large lead\u2010associated vegetations remains a clinical challenge.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We present the case of a 54\u2010year\u2010old woman with ischemic cardiomyopathy and recurrent ICD complications who developed bacteremia and infective endocarditis with vegetations on the aortic valve and a 1.5\u2009\u00d7\u20091.3\u2009cm mass on the right ventricular lead. Given her poor surgical candidacy due to worsening heart failure, a percutaneous approach was pursued.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The patient underwent successful intracardiac echocardiography (ICE)\u2010guided catheter\u2010based vegetation removal using a vacuum\u2010assisted aspiration system, followed by transvenous lead extraction. The procedure was well tolerated, and the patient demonstrated clinical improvement post intervention.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This case illustrates the utility of ICE\u2010guided percutaneous aspiration and lead extraction for managing large lead\u2010related vegetations in patients with infective endocarditis who are not candidates for surgery.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/joa3.70192","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T11:40:19Z","timestamp":1757677219000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Precision in Action: Using Intracardiac Echocardiography for Targeted Removal of a Large Lead\u2010Related Vegetation in a Patient With Infective Endocarditis"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9437-5909","authenticated-orcid":false,"given":"Muhammad","family":"Memon","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Henry Ford Health Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad","family":"Sabra","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Henry Ford Heart & Vascular Institute Henry Ford Hospital Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arfaat A.","family":"Khan","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine & Cardiac Electrophysiology Henry Ford Heart & Vascular Institute, Henry Ford Hospital Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192665"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.013801"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.12.041"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15625"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201071935\u2010w"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30967"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ\u2010D\u201024\u201000245"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.09.001"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29999"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13726"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz283"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000909"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.05.012"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.70192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:47:09Z","timestamp":1761662829000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.70192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,12]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/joa3.70192"],"URL":"https:\/\/doi.org\/10.1002\/joa3.70192","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"type":"print","value":"1880-4276"},{"type":"electronic","value":"1883-2148"}],"subject":[],"published":{"date-parts":[[2025,9,12]]},"assertion":[{"value":"2025-05-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70192"}}