{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T16:17:19Z","timestamp":1784564239667,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare demographic, clinical, and laboratory profiles and short\u2010term outcomes between pre\u2010existing (chronic) atrial fibrillation (AF) and newly diagnosed AF among patients admitted to coronary care units (CCUs) in Turkey, and to identify factors associated with in\u2010hospital mortality within AF subtypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter, prospective national registry analysis included 540 consecutive AF patients from 50 CCU centers across seven geographic regions in Turkey (MORCOR\u2010TURK National Registry; September 1\u201330, 2022). Patients were categorized as pre\u2010existing AF (documented AF prior to or at admission) or newly diagnosed AF (first detected during hospitalization). Demographics, comorbidities, admission diagnoses, laboratory biomarkers (including NT\u2010proBNP and hs\u2010troponin I), management, and outcomes were recorded. Multivariable logistic regression identified independent predictors of in\u2010hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Pre\u2010existing AF (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009324) had higher prevalences of diabetes mellitus (42.3% vs. 31.5%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012) and acute coronary syndromes (58.6% vs. 34.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Newly diagnosed AF (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009216) more frequently presented with heart failure (45.8% vs. 28.4%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and dyspnea (67.1% vs. 48.5%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Newly diagnosed AF exhibited higher inflammatory burden (CRP median 28.4 vs. 12.6\u2009mg\/L;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and lower hemoglobin (11.8\u2009\u00b1\u20092.1 vs. 12.9\u2009\u00b1\u20091.8\u2009g\/dL;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). NT\u2010proBNP was elevated in both groups and higher in newly diagnosed AF (median 4850 vs. 3240\u2009pg\/mL;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). In\u2010hospital mortality was greater with newly diagnosed AF (12.0% vs. 6.8%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.042). Independent mortality predictors included age, chronic kidney disease, cardiogenic shock, and log\u2010transformed NT\u2010proBNP, hs\u2010troponin I, and CRP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In Turkish CCUs, pre\u2010existing and newly diagnosed AF constitute distinct clinical phenotypes with differing presentations, biomarker profiles, and short\u2010term risk. Newly diagnosed AF is associated with greater inflammatory and hemodynamic stress and higher in\u2010hospital mortality. Biomarker\u2010enriched risk stratification may refine prognostication and guide targeted management within AF subtypes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70238","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T06:10:18Z","timestamp":1764396618000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Profiles and In\u2010Hospital Outcomes of Pre\u2010Existing Versus Newly Diagnosed Atrial Fibrillation in Coronary Care Units: Insights From the MORCOR\u2010TURK National Registry"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7280-5137","authenticated-orcid":false,"given":"Ertan","family":"Aydin","sequence":"first","affiliation":[{"name":"Giresun \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  Giresun T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed M\u00fcrsel","family":"\u00d6\u011f\u00fctveren","sequence":"additional","affiliation":[{"name":"Recep Tayyip Erdo\u011fan \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  Rize T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurbet \u00d6zge","family":"Mert","sequence":"additional","affiliation":[{"name":"Eski\u015fehir Osmangazi \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  Eski\u015fehir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehtap","family":"Yeni","sequence":"additional","affiliation":[{"name":"Isparta \u015eehir Hastanesi  Isparta T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevil","family":"G\u00fcla\u015fti","sequence":"additional","affiliation":[{"name":"Adnan Menderes \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  Aydin T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4669-7387","authenticated-orcid":false,"given":"U\u011fur","family":"K\u00fc\u00e7\u00fck","sequence":"additional","affiliation":[{"name":"\u00c7anakkale 18 Mart \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  \u00c7anakkale T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ba\u015far","family":"Candemir","sequence":"additional","affiliation":[{"name":"Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130brahim Halil","family":"Tanbo\u011fa","sequence":"additional","affiliation":[{"name":"Ni\u015fanta\u015f\u0131 \u00dcniversitesi T\u0131bbi Istatistik Anabilim Dal\u0131  Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Seyda","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Recep Tayyip Erdo\u011fan \u00dcniversitesi T\u0131p Fak\u00fcltesi Kardiyoloji Anabilim Dal\u0131  Rize T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.11.010"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001193"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.03.040"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2011.10.011"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw233"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.advms.2017.06.005"},{"issue":"2","key":"e_1_2_10_9_1","first-page":"190","article-title":"European Heart Rhythm Association (EHRA)\/European Association of Cardiovascular Prevention and Rehabilitation (EACPR) Position Paper on How to Prevent Atrial Fibrillation Endorsed by the Heart Rhythm Society (HRS) and Asia Pacific Heart Rhythm Society (APHRS)","volume":"19","author":"Gorenek B.","year":"2017","journal-title":"Europace"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut373"},{"issue":"6","key":"e_1_2_10_11_1","first-page":"724","article-title":"Racial Differences in Atrial Fibrillation\u2010Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study and Cardiovascular Health Study (CHS)","volume":"2","author":"Magnani J. 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