{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:26:35Z","timestamp":1773008795492,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The impact of protein\u2010energy malnutrition (PEM) on patients hospitalized for conventional pacemaker implantation remains poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We utilized the 2020\u2009U.S. National Inpatient Sample (NIS) database to evaluate the impact of PEM on the in\u2010hospital outcomes of patients who underwent conventional pacemaker implantation. Patients aged 18 and older were identified by ICD\u201010 CM and PCS codes. Multivariable survey logistic and linear regression analyses were employed to examine in\u2010hospital outcomes, including in\u2010patient mortality, system\u2010based outcomes, and post\u2010procedural complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 108\u2009020 patients were identified with 4315 (3.99%) diagnosed with PEM. The mean age of the cohort was 76\u2009years, and 47.5% were female. The overall mortality rate among patients undergoing pacemaker implantation was 1.07%. After adjusting for various patient and hospital confounding factors, PEM was significantly associated with an increased risk of in\u2010hospital mortality (aOR 3.30, 95% CI 2.33\u20134.88,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), prolonged hospital stay (\u03b2\n                      <jats:sub>LOS<\/jats:sub>\n                      7.89, 95% CI 6.88\u20138.90,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and an increased risk of various complications such as sepsis (aOR 2.56, 95% CI 1.56\u20134.19,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) along with other post\u2010procedural complications including bleeding\/anemia (aOR 2.48, 95% CI 1.98\u20133.10,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), pneumothorax (aOR 2.47, 95% CI 1.71\u20133.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and pericardial complications (aOR 1.65, 95% CI 1.14\u20132.40,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PEM was associated with an increased risk of in\u2010hospital mortality, extended hospital stays, and various post\u2010procedural complications in patients undergoing conventional pacemaker implantation. Hence, prompt identification and effective management of PEM are essential for improving post\u2010procedural outcomes in these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70279","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T06:41:07Z","timestamp":1769755267000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes of Patients Hospitalized for Conventional Pacemaker Implantation With Protein\u2010Energy Malnutrition"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0086-5269","authenticated-orcid":false,"given":"Phuuwadith","family":"Wattanachayakul","sequence":"first","affiliation":[{"name":"Department of Medicine Jefferson Einstein Hospital  Philadelphia Pennsylvania USA"},{"name":"Sidney Kimmel Medical College Thomas Jefferson University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pojsakorn","family":"Danpanichkul","sequence":"additional","affiliation":[{"name":"Department of Medicine Texas Tech University  Lubbock Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chalothorn","family":"Wannaphut","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Hawaii John A. Burns School of Medicine  Honolulu Hawaii USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza","family":"Tahir","sequence":"additional","affiliation":[{"name":"Department of Medicine Jefferson Einstein Hospital  Philadelphia Pennsylvania USA"},{"name":"Sidney Kimmel Medical College Thomas Jefferson University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Malin","sequence":"additional","affiliation":[{"name":"Department of Medicine Jefferson Einstein Hospital  Philadelphia Pennsylvania USA"},{"name":"Sidney Kimmel Medical College Thomas Jefferson University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thanathip","family":"Suenghataiphorn","sequence":"additional","affiliation":[{"name":"Department of Medicine Griffin Hospital  Derby Connecticut 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