{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:15:29Z","timestamp":1773008129233,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Prolonged QT interval is common in end\u2010stage renal disease (ESRD) on dialysis, but its long\u2010term cardiovascular (CV) implications remain unclear.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Using TriNetX network (2010\u20132024), we identified adults with ESRD on dialysis and categorized them by QTc status. After 1:1 propensity score matching (\n n<\/jats:italic>\n \u2009=\u20093428\/group), outcomes (hazard ratio [HR]) were assessed using Cox regression.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Prolonged QTc (>\u2009500\u2009ms) was associated with higher risk of all\u2010cause mortality (HR 1.67;\n p<\/jats:italic>\n \u2009<\u20090.001), MACEs (HR 1.40;\n p<\/jats:italic>\n \u2009<\u20090.001), cardiac arrest (HR 1.75;\n p<\/jats:italic>\n \u2009<\u20090.001), sustained ventricular arrhythmia (HR 1.66;\n p<\/jats:italic>\n \u2009<\u20090.001), new\u2010onset atrial fibrillation (HR 1.12;\n p<\/jats:italic>\n \u2009=\u20090.01), and acute myocardial infarction (HR 2.19;\n p<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n In ESRD patients on dialysis, prolonged QT interval was independently associated with adverse CV outcomes and mortality.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/joa3.70299","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:21:34Z","timestamp":1771474894000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Significance of Prolonged\n QTc<\/scp>\n Interval in Patients on Dialysis: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"42","author":[{"given":"Hoang Nhat","family":"Pham","sequence":"first","affiliation":[{"name":"Department of Medicine University of Arizona Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramzi","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Giauque","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Arizona Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed K.","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"},{"name":"Department of Medicine Boston Medical Center\u2010Brighton Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Dreher","sequence":"additional","affiliation":[{"name":"Department of Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis R.","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7118-2302","authenticated-orcid":false,"given":"Chadi","family":"Ayoub","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Arsanjani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"LeMond","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amitoj","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Arizona Tucson Arizona USA"},{"name":"Sarver Heart Center University of Arizona Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Sorajja","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona 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