{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T06:48:15Z","timestamp":1782715695005,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005035","name":"Biotronik","doi-asserted-by":"publisher","award":["FF075"],"award-info":[{"award-number":["FF075"]}],"id":[{"id":"10.13039\/501100005035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Right ventricular pacing increases the risk of dyssynchrony, which raises the need for more physiological pacing strategies. Left bundle branch area pacing (LBBAP) has emerged, with most early studies utilizing lumen\u2010less pacing leads. The feasibility and safety of LBBAP using conventional stylet\u2010driven pacing lead (SDL) have been reported. We present prospective multicenter data, particularly in Asian clinical settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The ACHIEVE\u2010SYNC pilot study was a multicenter prospective observational cohort study conducted across several tertiary hospitals in South Korea. Patients with standard indications for pacemaker implantation underwent LBBAP using a 5.6Fr SDL with an extendable screw. Procedural success rate and LBBAP\u2010related complications were evaluated. Pacing parameters, electrocardiographic features, and echocardiographic outcomes were assessed up to 12\u2009months after implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>LBBAP using SDL was successful in 100 of 101 (99.0%) patients. LBBAP lead\u2010related adverse event occurred in 1 case (0.99%), which was lead dislodgement. The median pacing threshold at 12\u2010month follow\u2010up was 0.8 [0.7\u20131.0] V at 0.5\u2009ms. At 12\u2010month follow\u2010up, the mean QRS duration changed from 119.2\u2009\u00b1\u200928.6\u2009ms to 131.2\u2009\u00b1\u200923.8\u2009ms. The mean left ventricular ejection fraction was 61.3%\u2009\u00b1\u20098.5% before the procedure and 61.3%\u2009\u00b1\u20097.5% at 12\u2010month follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this prospective multicenter registry, LBBAP using SDL demonstrated a near\u2010complete procedural success rate and a high incidence of confirmed Left bundle branch capture. Lead performance remained stable during long\u2010term follow\u2010up, and adverse events were rare, supporting the safety and technical feasibility of this approach in routine clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70345","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:44:23Z","timestamp":1777707863000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and Safety on Left Bundle Branch Area Pacing With Standard Stylet\u2010Driven Lead:\n                    <scp>ACHIEVE<\/scp>\n                    \u2010\n                    <scp>SYNC<\/scp>\n                    Multicenter Prospective Observational Cohort Study"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7799-104X","authenticated-orcid":false,"given":"Ga\u2010In","family":"Yu","sequence":"first","affiliation":[{"name":"Division of Cardiology, Gyeongsang National University Changwon Hospital Gyeongsang National University College of Medicine  Changwon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So\u2010Ryoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Seoul National University Hospital Seoul National University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4200-3456","authenticated-orcid":false,"given":"Tae\u2010Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Hospital Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Soo","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Asan Medical Center Ulsan University College of Medicine  Seoul Republic of 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