{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T08:42:23Z","timestamp":1789548143104,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008349","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","award":["ECR_2024_00004180"],"award-info":[{"award-number":["ECR_2024_00004180"]}],"id":[{"id":"10.13039\/100008349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic Chagas cardiomyopathy (CCC) exhibits high arrhythmic risk despite preserved systolic function, challenging LVEF\u2010based stratification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a cross\u2010sectional analysis of 146 heart failure patients (75 CCC, 71 Ischemic Cardiomyopathy [IC]) with comparable age, LVEF, and NT\u2010proBNP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      CCC patients had a higher arrhythmic burden and NSVT prevalence (RR 4.37, 95% CI 1.67\u201311.39). NSVT prevalence in CCC was similar regardless of LVEF (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.707). Conventional heart failure severity markers, including worse global and regional strain, were associated with NSVT in IC but not in CCC, where atrial fibrillation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) and ventricular aneurysms (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033) were the primary associated variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Arrhythmic vulnerability in CCC appears decoupled from LVEF, suggesting that complementary substrate\u2010based markers may improve risk stratification in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70365","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T06:35:08Z","timestamp":1779172508000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Electro\u2010Mechanical Dissociation in Chagas Cardiomyopathy: Comparative Analysis of Arrhythmic Burden Beyond\n                    <scp>LVEF<\/scp>"],"prefix":"10.1002","volume":"42","author":[{"given":"Luis E.","family":"Echeverr\u00eda","sequence":"first","affiliation":[{"name":"Heart Failure and Transplant Unit Fundaci\u00f3n Cardiovascular de Colombia  Floridablanca Colombia"},{"name":"Escuela de Medicina Universidad de Santander  Bucaramanga Colombia"},{"name":"Non\u2010Invasive Cardiovascular Imaging Unit Fundaci\u00f3n Cardiovascular de Colombia  Floridablanca Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyda 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