{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T06:48:13Z","timestamp":1782715693938,"version":"3.54.5"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003348","name":"Fukuda Foundation for Medical Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to explore the predictors of disease severity in patients with coronavirus disease 2019 (COVID\u201019) using ambulatory electrocardiographic markers (AECG\u2010Ms), which are prognostic predictors of cardiac death, as well as echocardiography and laboratory parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective cohort study was conducted using data from 70 patients diagnosed with COVID\u201019 and admitted to the National Defense Medical College Hospital between January 2021 and December 2023. A high\u2010resolution Holter electrocardiogram recorder was attached to all patients for 24\u2009h within 48\u2009h of admission, and AECG\u2010Ms were measured. Laboratory tests and echocardiography were also performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Logistic univariate analysis revealed that the T\u2010wave alternans (TWA) positivity rate was significantly higher in the fatal event group (all\u2010cause mortality and onset of sustained ventricular tachycardia or ventricular fibrillation) than in the non\u2010fatal event group. Kaplan\u2013Meier curves at 30\u2009days after admission showed a significant worsening in the survival rate of the TWA and late potential positive groups (log\u2010rank test,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) compared with the other groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients with COVID\u201019 without obvious cardiac disease, AECG\u2010Ms were highly positive. The study findings may allow easy and rapid prediction of prognosis at the bedside of patients with COVID\u201019.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70399","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T09:03:21Z","timestamp":1781859801000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Significance and Usefulness of High\u2010Resolution 24\u2010h Electrocardiographic Parameters in Patients With Coronavirus Disease 2019 After Admission: A Prospective Cohort Study"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8282-7633","authenticated-orcid":false,"given":"Motohiro","family":"Kimata","sequence":"first","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Saitama 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