{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:02:23Z","timestamp":1791295343033,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anemia is common in patients with atrial fibrillation (AF). Prior studies have associated anemia\u2014based on a single pre\u2010procedural hemoglobin measurement\u2014with AF recurrence after catheter ablation. However, it remains unclear whether chronic anemia confers a different risk compared with transient anemia. This study evaluated the association between transient and chronic anemia and AF recurrence following first\u2010time catheter ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this nationwide cohort study, we included 15\u2009017 patients from the Danish National Ablation Database undergoing first\u2010time AF ablation between 2010 and 2024 with available hemoglobin measurements within 12\u2009months prior to the procedure. Patients were categorized as having no anemia, transient anemia, or chronic anemia based on repeated hemoglobin measurements. The primary outcome was AF recurrence within 1\u2009year after a 90\u2010day blanking period, defined as a composite of AF\u2010related hospitalization, cardioversion, antiarrhythmic drug use, or repeat ablation. Associations were assessed using multivariable Cox proportional hazards models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 877 patients (5.8%) had chronic anemia and 1592 (10.6%) had transient anemia. During follow\u2010up, 3445 patients (23.6%) experienced AF recurrence. The 1\u2010year cumulative incidence of recurrence was highest in patients with chronic anemia (32.5%), followed by transient anemia (24.2%) and no anemia (23.0%). Compared with non\u2010anemic patients, chronic anemia was independently associated with an increased risk of AF recurrence (adjusted hazard ratio [HR]: 1.36; 95% confidence interval [CI]: 1.18\u20131.56), whereas transient anemia was not (HR: 0.98; 95% CI: 0.87\u20131.10).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Chronic\u2014but not transient\u2014anemia prior to first\u2010time catheter ablation was independently associated with a higher risk of AF recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/joa3.70445","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T05:49:16Z","timestamp":1786600156000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chronic but not Transient Anemia Is Associated With Atrial Fibrillation Recurrence After Catheter Ablation"],"prefix":"10.1002","volume":"42","author":[{"given":"Mikkel Guldberg","family":"Kasch","sequence":"first","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00fami Torpe","family":"Sn\u00e6bj\u00f6rnsson","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise Da","family":"Riis\u2010Vestergaard","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rogina","family":"Rached","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4029-1060","authenticated-orcid":false,"given":"Daniel M\u00f8lager","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"},{"name":"Department of Cardiology Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2220-0375","authenticated-orcid":false,"given":"Casper","family":"Binding","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"},{"name":"Department of Cardiology Copenhagen University Hospital\u2014Amager and Hvidovre  Copenhagen Denmark"},{"name":"Department of Cardiology Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0657-2176","authenticated-orcid":false,"given":"Mariam","family":"Elmegaard","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3423-5495","authenticated-orcid":false,"given":"Mads","family":"Hashiba","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian K.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Lambert","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2892-6131","authenticated-orcid":false,"given":"Christian","family":"Torp\u2010Pedersen","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Cardiology Copenhagen University Hospital\u2014North Zealand Hospital  Hillerod Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Schou","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0548-402X","authenticated-orcid":false,"given":"Gunnar","family":"Gislason","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2383-4609","authenticated-orcid":false,"given":"Abdullahi Ahmed","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Cardiology Copenhagen University Hospital\u2014Herlev and Gentofte  Copenhagen Denmark"},{"name":"Department of Cardiology Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2024.09.024"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae176"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.824789"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.008128"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-16938-6"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac692"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2015.04.002"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac225"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux013"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.09.029"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2020.100507"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-022-02633-6"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2024-325244"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.04.044"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1327387"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000163"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/sja.SJA_543_18"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/14017431.2022.2099009"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S245060"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S91125"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810393562"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyw213"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2015.07.006"},{"key":"e_1_2_11_26_1","volume-title":"Rstudio: Integrated Development Environment for R","author":"Rstudio Team","year":"2022"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.583570"}],"container-title":["Journal of Arrhythmia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.70445","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/joa3.70445","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/joa3.70445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:45:06Z","timestamp":1791294306000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/joa3.70445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/joa3.70445"],"URL":"https:\/\/doi.org\/10.1002\/joa3.70445","archive":["Portico"],"relation":{},"ISSN":["1880-4276","1883-2148"],"issn-type":[{"value":"1880-4276","type":"print"},{"value":"1883-2148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70445"}}