{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:01:08Z","timestamp":1791295268578,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Arrhythmia"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Advanced cardiac imaging can characterize infarct substrate and guide ablation strategy and lesion delivery during ventricular tachycardia (VT) ablation, but its incremental benefit over conventional strategies in ischemic cardiomyopathy (ICM) remains uncertain. We compared imaging\u2010guided with conventional VT ablation in adults with ICM. This PRISMA\u2010compliant systematic review and meta\u2010analysis was registered in PROSPERO (CRD420261399180). MEDLINE, Cochrane CENTRAL, and Scopus were searched from January 1, 2016, through May 21, 2026, with citation tracking. Comparative analyses were restricted to ICM populations or extractable ICM subgroups. The primary outcome was VT recurrence, pooled using random\u2010effects risk ratios (RRs); single\u2010arm imaging\u2010guided cohorts were summarized descriptively. Four comparative studies included 316 patients, of whom 134 underwent imaging\u2010guided ablation and 182 underwent conventional ablation. Imaging\u2010guided ablation was associated with lower VT recurrence (pooled RR 0.53, 95% confidence interval 0.36\u20130.79;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002;\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090%), with consistent effects across imaging modalities and study designs. Major complications were infrequent and numerically similar between groups, although sparse events and heterogeneous definitions precluded pooling. Three additional single\u2010arm imaging\u2010guided studies reported favorable VT\u2010free or event\u2010free survival, acceptable safety, and high acute non\u2010inducibility, but were not used to infer comparative efficacy. In patients with ICM undergoing scar\u2010related VT ablation, imaging\u2010guided ablation was associated with lower VT recurrence without an apparent increase in major complications; given the limited comparative evidence, these findings are hypothesis\u2010generating rather than practice\u2010changing. Larger multicenter randomized trials are required to confirm the magnitude of benefit and define patient selection, imaging modality, and integration strategy.\n                  <\/jats:p>","DOI":"10.1002\/joa3.70449","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:59:15Z","timestamp":1787317155000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Imaging\u2010Guided Versus Conventional Ventricular Tachycardia Ablation in Ischemic Cardiomyopathy: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5741-8019","authenticated-orcid":false,"given":"Sabbir","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Cardiology Worcestershire Acute Hospitals NHS Trust  Worcester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2643-0434","authenticated-orcid":false,"given":"Khalid","family":"Sawalha","sequence":"additional","affiliation":[{"name":"UMass Chan\u2010Baystate Medical Centre  Springfield Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8673-0386","authenticated-orcid":false,"given":"Mohamed","family":"Sharief","sequence":"additional","affiliation":[{"name":"Mersey and West Lancashire Teaching Hospitals NHS Foundation Trust  Prescot UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4798-8875","authenticated-orcid":false,"given":"Ahmed","family":"Ammar","sequence":"additional","affiliation":[{"name":"Department of Cardiology Worcestershire Acute Hospitals NHS Trust  Worcester UK"},{"name":"Department of Cardiology Ain Shams University  Cairo Egypt"},{"name":"Heart Rhythm Research Group, Division of Biomedical Sciences University of Warwick  Coventry 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