{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T07:18:58Z","timestamp":1785827938280,"version":"3.56.0"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T00:00:00Z","timestamp":1620864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Basic Microbiol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Curcumin nanoparticles were most recently considered in medical research because of their antibacterial properties. The main objective of the study was to develop the green synthesis and antibacterial activity of curcumin nanoparticles using <jats:italic>Curcuma longa<\/jats:italic>. The processing of curcumin nanoparticles was carried out after the collection, identification, and extraction of curcumin. The effect of a sample on the synthesis of nanoparticles, such as curcumin aqueous concentrations (5, 10, and 20\u2009mg\/ml) and curcumin nanoparticles (5, 10, and 20\u2009mg\/ml), and the antibacterial effect of these nanoparticles on <jats:italic>Escherichia coli, Staphylococcus aureus<\/jats:italic>,\u00a0<jats:italic>Pseudomonas aeruginosa, Klebsiella pneumoniae<\/jats:italic>, and the fungal strain <jats:italic>Aspergillus niger<\/jats:italic>. For examining antibacterial and anti\u2010fungal activity disc diffusion method was performed, followed by the zone of inhibition. According to X\u2010ray diffraction and scanning electron microscope analysis, nanoparticles have spherical shapes and size of 42.64\u2009nm. Results showed that a high dose of 20\u2009mg\/ml curcumin nanoparticles have more antibacterial activity than curcumin extracts in <jats:italic>E. coli<\/jats:italic> as it showed the largest diameter of zone of inhibition as compared to other doses. Other bacterial\u00a0and fungal strains also showed significant results but <jats:italic>E. coli<\/jats:italic> was most prominent. The biosynthesis of curcumin nanoparticles using an aqueous extract of <jats:italic>C. longa<\/jats:italic> is a clean, inexpensive, and safe method that has not been used any toxic substance and consequently does not have side effects. Since several pathogenic species have acquired antibiotic resistance, the combination of curcumin with various nanoparticles would be beneficial in the cure of pathogenic diseases.<\/jats:p>","DOI":"10.1002\/jobm.202100010","type":"journal-article","created":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T13:40:35Z","timestamp":1620913235000},"page":"603-611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Assessment of antibacterial and antifungal potential of <i>Curcuma longa<\/i> and synthesized nanoparticles: A comparative study"],"prefix":"10.1002","volume":"61","author":[{"given":"Mansoor Ahmed","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Bioinformatics and Biotechnology International Islamic University  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurain Baig","family":"Moghul","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Rawal Institute of Health Sciences Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU)  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maisra Azhar","family":"Butt","sequence":"additional","affiliation":[{"name":"Faculty of Rehabilitation and Allied Health Sciences Riphah International University  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0953-639X","authenticated-orcid":false,"given":"Mubin Mustafa","family":"Kiyani","sequence":"additional","affiliation":[{"name":"Shifa College of Medical Technology Shifa Tameer\u2010e\u2010Millat University  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibraheem","family":"Zafar","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences Shifa Tameer\u2010e\u2010Millat University  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Imran","family":"Bukhari","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics and Biotechnology International Islamic University  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2016.11.012"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2013.10.050"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2015.06.025"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2012.02.009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja029267j"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cis.2008.09.002"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/2228-5326-2-32"},{"key":"e_1_2_8_9_1","first-page":"159","article-title":"Bioinspired synthesis of silver nanoparticles","volume":"4","author":"Parashar UK","year":"2009","journal-title":"Dig J Nanomater Biostruct"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matlet.2008.06.051"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmrt.2020.06.074"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matlet.2012.01.083"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2009.05.018"},{"key":"e_1_2_8_14_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2011\/270974","article-title":"Biosynthesis of nanoparticles by microorganisms and their applications","volume":"2011","author":"Li X","year":"2011","journal-title":"J Nanomater"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762001000500026"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf072591j"},{"key":"e_1_2_8_17_1","first-page":"115","article-title":"Curcumin coated gold nanoparticles: synthesis, characterization, cytotoxicity, antioxidant activity and its comparison with citrate coated gold nanoparticles","volume":"4","author":"Shaabani E","year":"2017","journal-title":"Nanomed J"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnoncrysol.2018.08.015"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2016.08.050"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2020.1730815"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/ayu.AYU_24_18"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina55010010"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2018.04.002"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1515\/ntrev-2015-0001"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13205-015-0302-9"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2013.10.005"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau4679"},{"key":"e_1_2_8_28_1","first-page":"44","article-title":"Turmeric and curcumin: biological actions and medicinal applications","volume":"87","author":"Chattopadhyay I","year":"2004","journal-title":"Curr Sci"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/186864"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2853045"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopr.2013.06.003"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep24797"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b00879"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules191118283"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2018.07.059"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2015.12.038"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph14010011"}],"container-title":["Journal of Basic Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jobm.202100010","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jobm.202100010","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jobm.202100010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T10:11:52Z","timestamp":1693390312000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jobm.202100010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,13]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1002\/jobm.202100010"],"URL":"https:\/\/doi.org\/10.1002\/jobm.202100010","archive":["Portico"],"relation":{},"ISSN":["0233-111X","1521-4028"],"issn-type":[{"value":"0233-111X","type":"print"},{"value":"1521-4028","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,13]]},"assertion":[{"value":"2021-01-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}