{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:26:11Z","timestamp":1747149971084,"version":"3.40.5"},"reference-count":56,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T00:00:00Z","timestamp":1656892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Basic Microbiol"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Beauveria bassiana<\/jats:italic> has been widely used as an important biological control fungus for agricultural and forest pests, and clarifying the interaction mechanism between <jats:italic>B. bassiana<\/jats:italic> and its host will help to better exert the efficacy of the mycoinsecticide. Here, we proposed a novel pattern analysis (PA) method for analyzing time\u2010series data and applied it to a transcriptomic data set of <jats:italic>B. bassiana<\/jats:italic> infecting <jats:italic>Galleria mellonella<\/jats:italic>. We screened out 14 patterns including 868 genes, which had some characteristics that were not inferior to differentially expressed genes (DEGs). Compared with the previous analysis of this data set, we had three novel discoveries during <jats:italic>B. bassiana<\/jats:italic> infection, including overall downregulation of gene expression, the more critical first 24\u2009h, and enrichment of regulatory functions of downregulated genes. Our new PA method promises to be an important complement to DEGs analysis for time\u2010series transcriptomic data, and our findings enrich our knowledge of molecular mechanisms of fungal\u2013host interactions.<\/jats:p>","DOI":"10.1002\/jobm.202200155","type":"journal-article","created":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T19:23:48Z","timestamp":1656962628000},"page":"1274-1286","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Time\u2010series gene expression patterns and their characteristics of <i>Beauveria bassiana<\/i> in the process of infecting pest insects"],"prefix":"10.1002","volume":"62","author":[{"given":"Guochao","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Plant Protection Shandong Agricultural University  Tai'an China"},{"name":"School of Biological Engineering\/Institute of Digital Ecology and Health Huainan Normal University  Huainan Anhui China"},{"name":"Shandong Tobacco Research Institute Co., Ltd.  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5716-0126","authenticated-orcid":false,"given":"Jifeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Biological Engineering\/Institute of Digital Ecology and Health Huainan Normal University  Huainan Anhui China"},{"name":"Key Laboratory of Biology and Sustainable Management of Plant Diseases and Pests of Anhui Higher Education Institutes\/School of Plant Protection Anhui Agricultural University  Hefei China"},{"name":"State Key Laboratory of Pollution Control and Resource Reuse  Nanjing China"},{"name":"Key Laboratory of Industrial Dust Prevention and Control &amp; Occupational Health and Safety Ministry of Education  Huainan China"},{"name":"Anhui Shanhe Pharmaceutical Excipients Co., Ltd.  Huainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuo","family":"Yao","sequence":"additional","affiliation":[{"name":"Jinan Agricultural Technology Extension Service Center  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Computer Science\/School of Electronic Engineering Huainan Normal University  Huainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenxi","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering Northwest A&amp;F University  Xianyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lvyi","family":"Shao","sequence":"additional","affiliation":[{"name":"School of Biological Engineering\/Institute of Digital Ecology and Health Huainan Normal University  Huainan Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Jiang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biology and Sustainable Management of Plant Diseases and Pests of Anhui Higher Education Institutes\/School of Plant Protection Anhui Agricultural University  Hefei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maoye","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biology and Sustainable Management of Plant Diseases and Pests of Anhui Higher Education Institutes\/School of Plant Protection Anhui Agricultural University  Hefei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Tong","sequence":"additional","affiliation":[{"name":"School of Computer Science\/School of Electronic Engineering Huainan Normal University  Huainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujun","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Plant Protection Shandong Agricultural University  Tai'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.6364"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","unstructured":"BordaloMD GravatoC BelezaS CamposD LopesI PestanaJLT.Lethal and sublethal toxicity assessment ofBacillus thuringiensisvar.israelensisandbeauveria bassianabased bioinsecticides to the aquatic insectChironomus riparius. Sci Total Environ.2020;698:134155.","DOI":"10.1016\/j.scitotenv.2019.134155"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006183"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-016-2131-3"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0181-0"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof5020033"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02246-09"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1503200112"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.5266"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/wdev.344"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005961"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2014.02.024"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/insects3020492"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.25.022106.141615"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2013.04.011"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2020.1827886"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2020.101332"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-ento-031616-035509"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-7917.12706"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psra.2016.10.001"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-017-1456-0"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00409-06"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001264"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2008.07.011"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fgb.2009.03.001"},{"key":"e_1_2_9_27_1","first-page":"D613","article-title":"PHI\u2010base: the pathogen\u2010host interactions database","volume":"48","author":"Urban M","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep00483"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30856-1"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.051664-0"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf401703b"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jip.2021.107564"},{"key":"e_1_2_9_33_1","first-page":"680","article-title":"Prediction and analysis of candidate effectors from the genome of Beauveria bassiana","volume":"33","author":"Mei L","year":"2019","journal-title":"J Nuclear Agric Sci"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12223-018-0659-3"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504609102"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068185"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132129"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0152908"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/817508"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0036-z"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2000.4315"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2004.01.025"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.201900429"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa1074"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2655"},{"key":"e_1_2_9_46_1","first-page":"1","article-title":"The igraph software package for complex network research","volume":"1695","author":"Csardi G","year":"2006","journal-title":"InterJ, complex systems"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002515"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2015.00584"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.adgen.2015.11.003"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-7-191"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth283"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg1036"},{"key":"e_1_2_9_53_1","first-page":"334","article-title":"Gene expression analysis using fuzzy k\u2010means clustering","volume":"14","author":"Arima C","year":"2003","journal-title":"Genome Informatics"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.6026\/97320630002005"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-016-0296-3"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-3-81"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11427-017-9101-3"}],"container-title":["Journal of Basic Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jobm.202200155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jobm.202200155","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jobm.202200155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T12:21:49Z","timestamp":1692620509000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jobm.202200155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,4]]},"references-count":56,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/jobm.202200155"],"URL":"https:\/\/doi.org\/10.1002\/jobm.202200155","archive":["Portico"],"relation":{},"ISSN":["0233-111X","1521-4028"],"issn-type":[{"type":"print","value":"0233-111X"},{"type":"electronic","value":"1521-4028"}],"subject":[],"published":{"date-parts":[[2022,7,4]]},"assertion":[{"value":"2022-03-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}