{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:10:37Z","timestamp":1791421837204,"version":"4.3.3"},"reference-count":90,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Basic Microbiol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Under adverse environmental conditions, microorganisms are able to enter a state of cellular dormancy which consists of cell cycle arrest and interruption of multiplication. This process ensures their perpetuation in the infected host organism and enables the spread of disease. Throughout biological evolution, dormancy allowed microorganisms to persist in a harsh niche until favorable conditions for their reactivation were re\u2010established. Here, we propose to discuss the dormancy of bacteria and protozoa pathogens focusing on the potential mechanisms and components associated with dormancy.<\/jats:p>","DOI":"10.1002\/jobm.202300389","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T17:02:24Z","timestamp":1702054944000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cellular dormancy: A widespread phenomenon that perpetuates infectious diseases"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5052-3139","authenticated-orcid":false,"given":"Claudio V.","family":"da Silva","sequence":"first","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresiama","family":"Velikkakam","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elida C. M.","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna C. A.","family":"Silveira","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joed P.","family":"de Lima J\u00fanior","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelsa P. I.","family":"Uombe","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo H. R.","family":"da Silva","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna C.","family":"Borges","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.05.012"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.07307-11"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.12.6511-6518.2000"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-32-9449-3_3"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-3879(51)80038-2"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912765107"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099390"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000317"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3448"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt302"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/221838a0"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0023479"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.2.306"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00260-0"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.112408.134306"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1100186108"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03512.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.03027.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.24.8172-8180.2004"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.188.10.3494-3497.2006"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01237-06"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.12.3282"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01740-05"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.155.2.768-775.1983"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03779.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aat5750"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.05.011"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2020.01.102"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.06628-11"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063068"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuab042"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1914741117"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01117-08"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201408-1502OC"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2012.06.033"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.364851"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0001502"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2009.01325.x"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2013.07.004"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-015-2197-6"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.140106"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20040646"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10111417"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02944-22"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.1079569"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003634"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2373"},{"key":"e_1_2_10_49_1","first-page":"21","article-title":"A strain of Plasmodium vivax characterized by prolonged incubation: morphological and biological characteristics","volume":"52","author":"Garnham PC","year":"1975","journal-title":"Bull World Health Organ"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-10-297"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07327"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2375"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2018.06.026"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2019.02.007"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.29605"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.41081"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.986314"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj20031487"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(03)00137-3"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M708949200"},{"key":"e_1_2_10_61_1","unstructured":"MaherSP BakowskiMA VantauxA FlanneryEL AndolinaC GuptaM et al.A drug repurposing approach reveals targetable epigenetic pathways inPlasmodium vivaxhypnozoites.bioRxiv.20232023.01.31.526483."},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2017.12.003"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00347-16"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00054-17"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007035"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12121"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1300059110"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.35.21661"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1128\/EC.05117-11"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M800681200"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj20040262"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.12.013"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-141"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2013.01.039"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000920"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2014.04.011"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.13048"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2017.08.006"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00755-16"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022492"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2005.08.014"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01236-15"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-015-4807-2"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-35267-5"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34039"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abb7656"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00673-18"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00005"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-019-06554-w"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.200261"},{"key":"e_1_2_10_91_1","first-page":"6","article-title":"New benznidazole regimes: hope for shorter, safer and more effective treatments for chagas disease","volume":"11","author":"DNDi","year":"2021","journal-title":"Newsl Chagas Dis Clin Res Platf"}],"container-title":["Journal of Basic Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jobm.202300389","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T06:11:44Z","timestamp":1714630304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jobm.202300389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,8]]},"references-count":90,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/jobm.202300389"],"URL":"https:\/\/doi.org\/10.1002\/jobm.202300389","archive":["Portico"],"relation":{},"ISSN":["0233-111X","1521-4028"],"issn-type":[{"value":"0233-111X","type":"print"},{"value":"1521-4028","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,8]]},"assertion":[{"value":"2023-07-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2300389"}}