{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T22:44:41Z","timestamp":1759099481034},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,1,10]],"date-time":"2007-01-10T00:00:00Z","timestamp":1168387200000},"content-version":"vor","delay-in-days":6583,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Basic Microbiol."],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Spirochetal organisms were sought in 18 skin and 4 synovial membrane specimens obtained by biopsy from 22 Lyme disease patients. The presence of spirochetes in body tissues was histologically demonstrated in one patient with lymphadenosis benigna cutis, one patient with acrodermatitis chronica atrophicans and in one patient with active arthritis. The organisms were 5\u201330 \u03bcm long and 0.12\u20130.25 \u03bcm thick, had 8 or 11 flagella arising from both ends of the body, and their ultrastructure was analogous to that of cultured <jats:italic>Borrelia burgdorferi<\/jats:italic> strains. They were located intra\u2010 or perivascularly, or in the collagenous connective tissue of the skin and synovium. This implies that Lyme spirochetes may have a potential to survive in body tissues and cause injury to blood vessels.<\/jats:p>","DOI":"10.1002\/jobm.3620290203","type":"journal-article","created":{"date-parts":[[2007,2,5]],"date-time":"2007-02-05T19:18:09Z","timestamp":1170703089000},"page":"73-83","source":"Crossref","is-referenced-by-count":21,"title":["Ultrastructure of <i>Borrelia burgdorferi<\/i> in tissues of patients with Lyme disease"],"prefix":"10.1002","volume":"29","author":[{"given":"Dagmar","family":"Hul\u00ednsk\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Jirou\u0161","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marika","family":"Vale\u0161ov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Herzogov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,10]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198303313081302"},{"key":"e_1_2_1_3_1","first-page":"162","article-title":"Spirochetenkleuring volgens \u201cGabriel Steiner\u201d","volume":"5","author":"Bosma R. B.","year":"1984","journal-title":"Histotechnick"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7043737"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198700111-00005"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/149.5.789"},{"key":"e_1_2_1_7_1","first-page":"543","article-title":"Ultrastructure of spirochetes isolated from Ixodes ricinus and Ixodes dammini","volume":"57","author":"Hovind\u2010Hougen K.","year":"1984","journal-title":"Yale J. Biol. Med."},{"key":"e_1_2_1_8_1","unstructured":"Jirou\u0161 J. Pokorn\u00fd J. Doutl\u00edk S. Bojar M.andHercogov\u00e1 J. 1987.Serologic diagnosis of the Lyme disease in Czechoslovakia. In: Book of abstracta IIIrdEuropean Congress of Clinical Microbiology Hague May 199\u2013200."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-23-3-261"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1128\/iai.46.1.220-223.1984","article-title":"Experimental Lyme disease in rabbits: spirochetes found in erythema migrans and blood","volume":"46","author":"Kornblatt A. N.","year":"1984","journal-title":"Infection and Immunity."},{"key":"e_1_2_1_11_1","first-page":"325","volume-title":"Medical Hypotheses","author":"Kurtz S. K.","year":"1986"},{"key":"e_1_2_1_12_1","first-page":"26","article-title":"Lyme arthritis. Spirochetes found in synovial microangiopathic lesions","volume":"118","author":"Johnston Y. E.","year":"1985","journal-title":"Am. J. of Pathol."},{"key":"e_1_2_1_13_1","first-page":"591","article-title":"Lyme arthritis. An epidemic of oligoartticular arthritis in children and adults in three Connectitut communities","volume":"238","author":"Steere A. C.","year":"1977","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198303313081301"},{"key":"e_1_2_1_15_1","unstructured":"Weber K. Schierz G. Wilske B.andPreac Mursic V. 1984.European erythema migrans diseases and related disorder. In: Steere A. C. et al. Lyme disease: first international symposium New Haven. Yale J. Biol. Med. 1984 15\u201321."},{"key":"e_1_2_1_16_1","first-page":"571","article-title":"Zur Klinik und \u00c4tiologie der Acrodermatitis chronica atrophicans","volume":"35","author":"Weber K.","year":"1984","journal-title":"Hautarzt"}],"container-title":["Journal of Basic Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjobm.3620290203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jobm.3620290203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T12:14:04Z","timestamp":1697976844000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jobm.3620290203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,1]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,1]]}},"alternative-id":["10.1002\/jobm.3620290203"],"URL":"https:\/\/doi.org\/10.1002\/jobm.3620290203","archive":["Portico"],"relation":{},"ISSN":["0233-111X","1521-4028"],"issn-type":[{"value":"0233-111X","type":"print"},{"value":"1521-4028","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,1]]}}}