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The defect of the <jats:italic>htp<\/jats:italic>R gene leads to some changes in ultrastructure of bacterial colonies and the intensification of the processes of development and aging of colonies as integral structures. These phenomena are manifested by early formation of intercellular contacts and thick surface films as well as the enhanced destruction of microorganisms. The recombinant <jats:italic>Shigella<\/jats:italic> strain grown at 30 \u00b0C retained its ability to provoke keratoconjunctivitis.<\/jats:p>","DOI":"10.1002\/jobm.3620330210","type":"journal-article","created":{"date-parts":[[2007,2,5]],"date-time":"2007-02-05T21:27:48Z","timestamp":1170710868000},"page":"131-139","source":"Crossref","is-referenced-by-count":4,"title":["Morpho\u2010physiologic characteristics of <i>Escherichia coli<\/i> and <i>Shigella flexneri<\/i> 2a carrying the <i>htp<\/i>R15 gene"],"prefix":"10.1002","volume":"33","author":[{"given":"Victor V.","family":"Tetz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oksana V.","family":"Rybalchenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Galina A.","family":"Savkova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(84)90493-8"},{"key":"e_1_2_1_3_1","first-page":"287","volume-title":"Analytical Physiology of Cells and Developing Organisms","author":"Goodwin B. 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