{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T10:54:15Z","timestamp":1769684055337,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,2,18]],"date-time":"2005-02-18T00:00:00Z","timestamp":1108684800000},"content-version":"vor","delay-in-days":5223,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[1990,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied the occurrence, magnitude, and kinetics of bacteremia and the resultant osteomyelitis and septic arthritis in an avian model of <jats:italic>Staphylococcus aureus<\/jats:italic> infection. Thirty\u2010day\u2010old male broiler chicks were inoculated i.v. with 10<jats:sup>5<\/jats:sup>, 10<jats:sup>6<\/jats:sup>, or 10<jats:sup>7<\/jats:sup> cfu of strain Duntravis, a \u03b2\u2010hemolytic, coagulaseproducing, capsular type 8 isolate from the synovial fluid of a 2\u2010year\u2010old black boy. Bacteremia occured in 80%, 90%, and 100% of animals inoculated with 10<jats:sup>5<\/jats:sup>, 10<jats:sup>6<\/jats:sup>, or 10<jats:sup>7<\/jats:sup> cfu, respectively. The magnitude of bacteremia in surviving, bacteremic animals increased for 96 hours after inoculation and then decreased after a plateau phase. Osteomyelitis and septic arthritis occurred only in chicks that were continuously bacteremic. The occurrence of osteomyelitis was uniform among continuously bacteremic animals and developed 1 to 23 hours after inoculation. Chickens are susceptible to systemic infections with <jats:italic>S. aureus<\/jats:italic>. Bacteremia, osteomyelitis, and septic arthritis may be induced in healthy chickens without prior manipulations that depress their resistance.<\/jats:p>","DOI":"10.1002\/jor.1100080605","type":"journal-article","created":{"date-parts":[[2005,2,24]],"date-time":"2005-02-24T11:54:01Z","timestamp":1109246041000},"page":"804-813","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["A model of <i>Staphylococcus aureus<\/i> bacteremia, septic arthritis, and osteomyelitis in chickens"],"prefix":"10.1002","volume":"8","author":[{"given":"Robert S.","family":"Daum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. Hodges","family":"Davis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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