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The mineral content and the total amount of EDTA\u2010extractable noncollagenous proteins, insulin\u2010like growth factor\u2010I, and osteocalcin were determined for the lengthened callus, and a gradient density fractionation analysis of bone powder particles was performed. The results were compared with two other areas of the lengthened tibia and one region of the contralateral tibia. The mineral and osteocalcin contents showed significant decreases, whereas the hydroxyproline concentration was significantly increased. 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