{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:18:48Z","timestamp":1762100328354},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,2,18]],"date-time":"2005-02-18T00:00:00Z","timestamp":1108684800000},"content-version":"vor","delay-in-days":2666,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[1997,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A fast, reproducible, and noninvasive method is required for quantifying cartilage thickness clinically and for studying the deformation of articular cartilage during and after mechanical loading <jats:italic>in vivo<\/jats:italic>. The objective of the current investigation was to test the repeatability of regional distribution patterns of patellar cartilage thickness in the living on the basis of a fat\u2010suppressed magnetic resonance imaging sequence with a short acquisition time and three\u2010dimensional digital data processing. The knees of eight healthy volunteers were transversally imaged with a fat\u2010suppressed FLASH\u20103D (fast low angle shot) sequence (acquisition time: 4 minutes and 10 seconds). In each case, the joint was newly positioned before each of the six replicate measurements was taken. The patellar cartilage was reconstructed three\u2010dimensionally, and the distribution of cartilage thickness was determined with a three\u2010dimensional minimal\u2010distance algorithm. Whereas the cartilage volume ranged from 3,198 to 7,149 mm<jats:sup>3<\/jats:sup>, the mean coefficient of variation for the 6\u2010fold volume measurement was 1.35%. On average, 75.1% (\u00b14.1%) of all test pixels could be attributed to the same cartilage thickness interval (0.5 mm) by image analysis; 14.8% (\u00b12.4%) deviated by one interval; 6.6% (\u00b11.5%), by two intervals; and 3.5% (\u00b11.8%), by more than two intervals. We conclude that, on the basis of a magnetic resonance imaging sequence with an acquisition time of less than 5 minutes, the quantitative distribution of cartilage thickness can be determined with high precision <jats:italic>in vivo<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/jor.1100150604","type":"journal-article","created":{"date-parts":[[2005,2,24]],"date-time":"2005-02-24T10:52:25Z","timestamp":1109242345000},"page":"808-813","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Repeatability of patellar cartilage thickness patterns in the living, using a fat\u2010suppressed magnetic resonance imaging sequence with short acquisition time and three\u2010dimensinal data 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