{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T09:45:21Z","timestamp":1698659121653},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,2,18]],"date-time":"2005-02-18T00:00:00Z","timestamp":1108684800000},"content-version":"vor","delay-in-days":1997,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[1999,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe a gene (PT\u201012) that is expressed in the patellar tendon and not in the anterior cruciate ligament. We used a recently developed polymerase chain reaction\u2010based subtractive cDNA analysis to discover genes that are overexpressed in the patellar tendon but not expressed in the anterior cruciate ligament; the long\u2010term objective was to find genes that are central to the self\u2010repair of the patellar tendon, in contrast with the inability of the anterior curciate ligament to launch a repair response following injury. PT\u201012 is a homologue of human S2 or mouse LLRep3 ribosomal genes, which are known to be overexpressed in highly proliferating cells. This study opens a new vista to the development of techniques and reagents to study the differences between two periarticular tissues (i.e., the patellar tendon and anterior cruciate ligament) that differ primarily in their ability to self\u2010repair.<\/jats:p>","DOI":"10.1002\/jor.1100170519","type":"journal-article","created":{"date-parts":[[2005,2,24]],"date-time":"2005-02-24T10:32:02Z","timestamp":1109241122000},"page":"745-747","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["PT\u201012, a putative ras\u2010activated proliferation\u2010dependent gene, is expressed in patellar tendon and not in anterior cruciate ligament"],"prefix":"10.1002","volume":"17","author":[{"given":"R. S.","family":"Goomer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Maris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Ostrander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Amiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100010305"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100040204"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100070405"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199506000-00008"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354657900700601"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354657900700105"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(39)90866-4"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mc.2940050309"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-196811000-00014"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0030-5898(20)31180-9","article-title":"Reconstruction of the anterior cruciate ligament","volume":"7","author":"Eriksson E","year":"1976","journal-title":"Orthop Clin North Am"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00003086-198003000-00006","article-title":"The natural history and diagnosis of anterior cruciate ligament insufficiency","volume":"147","author":"Fetto JF","year":"1980","journal-title":"Clin Orthop"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354658301100602"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/03008209409061973"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002239900474"},{"key":"e_1_2_1_16_2","first-page":"85","volume-title":"The Anterior Cruciate Ligament: Current and Future Concepts","author":"Hollis J","year":"1993"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/22.25.5640"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196345050-00003"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100040410"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(86)80022-6"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-199506000-00010"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-196709000-00002"},{"key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00003086-198301000-00014","article-title":"Intra\u2010articular cruciate reconstruction. I. Perspectives on graft strength, vascularization, and immediate motion after replacement","volume":"172","author":"Noyes FR","year":"1983","journal-title":"Clin Orthop"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-198410000-00002"},{"key":"e_1_2_1_25_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2106\/00004623-195537010-00001","article-title":"An analysis of end results of surgical treatment of major injuries to the ligaments of the knee","volume":"37","author":"O'Donoghue DH","year":"1955","journal-title":"J Bone Joint Surg [Am]"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196648030-00009"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197153040-00010"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.14.3867"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.3109\/03008209709160209"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/14.1.163"},{"key":"e_1_2_1_31_2","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1302\/0301-620X.66B5.6501359","article-title":"Replacement of the anterior cruciate ligament by an allogenic tendon graft: an experimental study in the dog","volume":"66","author":"Shino K","year":"1984","journal-title":"J Bone Joint Surg [Br]"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100090603"},{"key":"e_1_2_1_33_2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00003086-198301000-00013","article-title":"Primary repair of the anterior cruciate ligament","volume":"172","author":"Warren RF","year":"1983","journal-title":"Clin Orthop"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100150217"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjor.1100170519","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.1100170519","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T12:28:22Z","timestamp":1698582502000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.1100170519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,9]]}},"alternative-id":["10.1002\/jor.1100170519"],"URL":"https:\/\/doi.org\/10.1002\/jor.1100170519","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,9]]},"assertion":[{"value":"1998-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-03-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-02-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}