{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:25:36Z","timestamp":1790839536601,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2009,2,25]],"date-time":"2009-02-25T00:00:00Z","timestamp":1235520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Our objective was to characterize variations in mechanical knee alignment, tibial torsion, tibial width, and ACL laxity measurements between Japanese and Caucasian populations in the healthy, young adult knee joint. Seventy young adult subjects participated in this study, including 23 Japanese and 47 Caucasian subjects. Coronal magnetic resonance images of the hip, knee, and ankle were acquired for analysis. Japanese subjects had a significantly higher (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.04) varus alignment (1.64 \u00b1 0.43\u00b0 standard error) than Caucasians (0.55 \u00b1 0.33\u00b0), while women exhibited a more valgus alignment (0.16 \u00b1 0.52\u00b0) than men (0.94 \u00b1 0.42\u00b0,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.04). Significant differences were found in tibial torsion and ACL laxity (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01) between ethnicities, with Japanese exhibiting lower tibial torsion (33.4 \u00b1 10.0\u00b0) and higher ACL laxity (7.5 \u00b1 0.4 mm) measurements compared to Caucasians (38.9 \u00b1 9.5\u00b0 and 5.7 \u00b1 0.3 mm, respectively). Significant differences between genders were found in hip\u2010knee\u2010ankle alignment (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.04), tibial width (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.0001), and ACL laxity (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01) measurements. Measurements were reliable between observers and for repeated positioning. Our study provides new insight into anatomical and geometric differences in the knee joint between Japanese and Caucasians, as well as between females and males. Further consideration of these results may improve development of implants to accommodate for these differences, and understanding of characteristics leading to increased prevalence of knee OA in certain populations. The use of magnetic resonance imaging to obtain these measurements also allows soft tissue structure characterization without exposure to ionizing radiation. \u00a9 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. 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