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Using micro\u2010CT cadaver images, a finite element model of the glenohumeral joint was generated, consisting of humerus, glenoid bone, cartilages, labrum, and biceps tendon. A glenohumeral compression of 50\u2009N and biceps tensions of 0, 22, 55, and 88\u2009N were applied. The humeral head was superiorly translated from 0 to 5\u2009mm in 1\u2010mm increments. The highest labral strain occurred at the interface with the glenoid cartilage and bone beneath the origin of the biceps tendon. The maximum strain was lower than the reported failure strain. The humeral head motion had relatively greater effect than biceps tension on the increasing labral strain. This supports the mechanistic hypothesis that superior labral lesions result mainly from superior migration of the humeral head, but also from biceps tension. \u00a9 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. 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