{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T10:17:51Z","timestamp":1789813071381,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T00:00:00Z","timestamp":1428278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T00:00:00Z","timestamp":1428278400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Health and Welfare Research Grant","award":["H23-007"],"award-info":[{"award-number":["H23-007"]}]},{"name":"Health and Welfare Research Grant","award":["H24-001"],"award-info":[{"award-number":["H24-001"]}]},{"name":"Health and Welfare Research Grant","award":["H26-006"],"award-info":[{"award-number":["H26-006"]}]},{"name":"Japanese Ministry of Health, Labour and Welfare"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      The use of larger femoral heads to prevent the dislocation of artificial hip joints has recently become more common. However, concerns about the subsequent use of thinner polyethylene liners and their effects on wear rate have arisen. Previously, we prepared and evaluated the biological and mechanical effects of a novel highly cross\u2010linked polyethylene (CLPE) liner with a nanometer\u2010scaled graft layer of poly(2\u2010methacryloyloxyethyl phosphorylcholine) (PMPC). Our findings showed that the PMPC\u2010grafted particles were biologically inert and caused no subsequent bone resorptive responses and that the PMPC\u2010grafting markedly decreased wear in a hip joint simulator. However, the metal or ceramic femoral heads used in this previous study had a diameter of 26\u2009mm. Here, we investigated the wear\u2010resistance of the PMPC\u2010grafted CLPE liner with a 40\u2010mm femoral head during 10\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      cycles of loading in the hip joint simulator. The results provide preliminary evidence that the grafting markedly decreased gravimetric wear rate and the volume of wear particles, even when coupled with larger femoral heads. Thus, we believe the PMPC\u2010grafting will prolong artificial hip joint longevity both by preventing aseptic loosening and by improving the stability of articular surface. \u00a9 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1103\u20131110, 2015.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jor.22868","type":"journal-article","created":{"date-parts":[[2015,3,12]],"date-time":"2015-03-12T07:00:38Z","timestamp":1426143638000},"page":"1103-1110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Wear resistance of the biocompatible phospholipid polymer\u2010grafted highly cross\u2010linked polyethylene liner against larger femoral head"],"prefix":"10.1002","volume":"33","author":[{"given":"Toru","family":"Moro","sequence":"first","affiliation":[{"name":"Division of Science for Joint Reconstruction, Graduate School of Medicine The University of Tokyo 7\u20103\u20101 Hongo, Bunkyo\u2010ku Tokyo 113\u20108655 Japan"},{"name":"Sensory &amp; Motor System Medicine, Faculty of Medicine The University of Tokyo 7\u20103\u20101 Hongo, Bunkyo\u2010ku Tokyo 113\u20108655 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3\u20103\u201031 Miyahara, Yodogawa\u2010ku Osaka 532\u20100003 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, School of Engineering The University of Tokyo 7\u20103\u20101 Hongo, Bunkyo\u2010ku Tokyo 113\u20108656 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kawaguchi","sequence":"additional","affiliation":[{"name":"Japan Community Health care Organization Tokyo Shinjuku Medical Center, Spine Center 5\u20101 Tsukudo, Shinjuku\u2010ku Tokyo 162\u20108543 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masami","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Materials Research and Development Laboratory Japan Fine Ceramics Center 2\u20104\u20101 Mutsuno, Atsuta\u2010ku Nagoya 456\u20108587 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