{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:45:41Z","timestamp":1757778341250,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["132971","142669"],"award-info":[{"award-number":["132971","142669"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Culture"},{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Orthop. Res."],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1002\/jor.23073","type":"journal-article","created":{"date-parts":[[2015,10,19]],"date-time":"2015-10-19T13:58:50Z","timestamp":1445263130000},"page":"836-844","source":"Crossref","is-referenced-by-count":17,"title":["Eradication of osteosarcoma by fluorescence-guided surgery with tumor labeling by a killer-reporter adenovirus"],"prefix":"10.1002","volume":"34","author":[{"given":"Shuya","family":"Yano","sequence":"first","affiliation":[{"name":"AntiCancer; Inc.; San Diego California"},{"name":"Department of Surgery; University of California; San Diego California"},{"name":"Department of Gastroenterological Surgery; Graduate School of Medicine; Dentistry and Pharmaceutical Sciences; Okayama University; Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Miwa","sequence":"additional","affiliation":[{"name":"AntiCancer; Inc.; San Diego California"},{"name":"Department of Surgery; University of California; San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kishimoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery; Graduate School of Medicine; Dentistry and Pharmaceutical Sciences; Okayama University; Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Urata","sequence":"additional","affiliation":[{"name":"Oncolys BioPharm Inc.; Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Tazawa","sequence":"additional","affiliation":[{"name":"Center for Innovative Clinical Medicine; Okayama University Hospital; Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Kagawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery; Graduate School of Medicine; Dentistry and Pharmaceutical Sciences; Okayama University; Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Bouvet","sequence":"additional","affiliation":[{"name":"Department of Surgery; University of California; San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyoshi","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery; Graduate School of Medicine; Dentistry and Pharmaceutical Sciences; Okayama University; Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"AntiCancer; Inc.; San Diego California"},{"name":"Department of Surgery; University of California; San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,11,3]]},"reference":[{"key":"10.1002\/jor.23073-BIB0001|jor23073-cit-0001","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1002\/cncr.21724","article-title":"Prognostic factors for osteosarcoma of extremity treated with neoadjuvant chemotherapy: 15-year experience in 789 patients treated at a single institution","volume":"106","author":"Bacci","year":"2006","journal-title":"Cancer"},{"key":"10.1002\/jor.23073-BIB0002|jor23073-cit-0002","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1200\/JCO.20.3.776","article-title":"Prognostic factors in high-grade osteosarcoma of extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols","volume":"20","author":"Bielack","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1002\/jor.23073-BIB0003|jor23073-cit-0003","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1002\/jor.22706","article-title":"Fluorescence-guided surgery improves outcome in an orthotopic osteosarcoma nude-mouse model","volume":"32","author":"Miwa","year":"2014","journal-title":"J Orthopaedic Res"},{"key":"10.1002\/jor.23073-BIB0004|jor23073-cit-0004","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1038\/nm1404","article-title":"In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus","volume":"12","author":"Kishimoto","year":"2006","journal-title":"Nat Med"},{"key":"10.1002\/jor.23073-BIB0005|jor23073-cit-0005","doi-asserted-by":"crossref","first-page":"14514","DOI":"10.1073\/pnas.0906388106","article-title":"In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation","volume":"106","author":"Kishimoto","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/jor.23073-BIB0006|jor23073-cit-0006","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.4161\/cc.10.16.16756","article-title":"Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection","volume":"10","author":"Kishimoto","year":"2011","journal-title":"Cell Cycle"},{"key":"10.1002\/jor.23073-BIB0007|jor23073-cit-0007","doi-asserted-by":"crossref","first-page":"13133","DOI":"10.18632\/oncotarget.3811","article-title":"Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma","volume":"6","author":"Yano","year":"2015","journal-title":"Oncotarget"},{"key":"10.1002\/jor.23073-BIB0008|jor23073-cit-0008","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1038\/mt.2015.63","article-title":"Experimental curative fluorescence-guided surgery of highly invasive glioblastoma multiforme selectively labeled with a killer-reporter adenovirus","volume":"23","author":"Yano","year":"2015","journal-title":"Mol Ther"},{"key":"10.1002\/jor.23073-BIB0009|jor23073-cit-0009","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/cgt.2015.26","article-title":"Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery","volume":"22","author":"Yano","year":"2015","journal-title":"Cancer Gene Ther"},{"key":"10.1002\/jor.23073-BIB0010|jor23073-cit-0010","doi-asserted-by":"crossref","first-page":"e000096","DOI":"10.1136\/bmjresp-2015-000096","article-title":"Precise navigation surgery of tumors in the lung in mouse models enabled by in situ fluorescence labeling with a killer-reporter adenovirus","volume":"2","author":"Yano","year":"2015","journal-title":"BMJ Open Respiratory Research"},{"key":"10.1002\/jor.23073-BIB0011|jor23073-cit-0011","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1002\/jor.22706","article-title":"Fluorescence-guided surgery improves outcome in an orthotopic osteosarcoma nude-mouse model","volume":"32","author":"Miwa","year":"2014","journal-title":"J Orthop Res"},{"key":"10.1002\/jor.23073-BIB0012|jor23073-cit-0012","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/jcb.22259","article-title":"In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential","volume":"108","author":"Tome","year":"2009","journal-title":"J Cell Biochem"},{"key":"10.1002\/jor.23073-BIB0013|jor23073-cit-0013","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1002\/jcb.23122","article-title":"The bulge area is the origin of nestin-expressing pluripotent stem cells of the hair follicle","volume":"112","author":"Uchugonova","year":"2011","journal-title":"J Cell Biochem"},{"key":"10.1002\/jor.23073-BIB0014|jor23073-cit-0014","doi-asserted-by":"crossref","first-page":"4208","DOI":"10.1158\/0008-5472.CAN-05-3927","article-title":"Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system","volume":"66","author":"Yamauchi","year":"2006","journal-title":"Cancer Res"},{"key":"10.1002\/jor.23073-BIB0015|jor23073-cit-0015","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2184.2009.00652.x","article-title":"Targeted therapy of spinal cord glioma with a genetically-modified Salmonella typhimurium","volume":"43","author":"Kimura","year":"2010","journal-title":"Cell Prolif"},{"key":"10.1002\/jor.23073-BIB0016|jor23073-cit-0016","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/mt.2009.262","article-title":"A phase I study of telomerase-specific replication competent oncolytic adenovirus (telomelysin) for various solid tumors","volume":"18","author":"Nemunaitis","year":"2010","journal-title":"Mol Ther"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjor.23073","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jor.23073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T12:06:17Z","timestamp":1625486777000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.23073"}},"subtitle":["KILLER-REPORTER ADENOVIRUS FOR OSTEOSARCOMA FGS"],"short-title":[],"issued":{"date-parts":[[2015,11,3]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"URL":"https:\/\/doi.org\/10.1002\/jor.23073","archive":["Portico"],"relation":{},"ISSN":["0736-0266"],"issn-type":[{"type":"print","value":"0736-0266"}],"subject":[],"published":{"date-parts":[[2015,11,3]]}}}